HitPredict

Interactor 1: THIO (P10599)
Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP) (allergen Hom s Trx)
Gene: TXN

Interactor 2: CEBPA (P49715)
CCAAT/enhancer-binding protein alpha (C/EBP alpha)
Gene: CEBPA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.27	0.60	0.408

Property	Details
Experiments	34189442
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0042803 - protein homodimerization activity
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 105 Hs			1 358
+	Hs
		202606 TXNL1_HUMAN (2-105): 1.99e-36: 126: 40.39		CEBPA_HUMAN (1-358): 1.35e-69: 223: 100.00
+	Hs
		831497 TXND5_HUMAN (12-105): 2.13e-27: 105: 27.00		CEBPA_HUMAN (1-358): 1.35e-69: 223: 100.00
+	Hs
		531759 PDIA4_HUMAN (3-104): 4.21e-25: 99.4: 23.85		CEBPA_HUMAN (1-358): 1.35e-69: 223: 100.00
+	Hs
		495455 THIO_HUMAN (1-105): 6.33e-41: 132: 100.00		CEBPB_HUMAN (51-357): 3.68e-47: 164: 31.61
+	Hs
		569878 TXND5_HUMAN (12-105): 2.13e-27: 105: 27.00		CEBPB_HUMAN (51-357): 3.68e-47: 164: 31.61
+	Hs
		531714 PDIA4_HUMAN (3-104): 4.21e-25: 99.4: 23.85		CEBPB_HUMAN (51-357): 3.68e-47: 164: 31.61
+	Hs
		423137 PDIA1_HUMAN (2-103): 7.44e-23: 92.9: 22.22		CEBPB_HUMAN (51-357): 3.68e-47: 164: 31.61
+	Hs
		547829 TXND5_HUMAN (12-105): 2.13e-27: 105: 27.00		ATF2_HUMAN (46-352): 2.46e-30: 122: 10.97
+	Hs
		531705 PDIA4_HUMAN (3-104): 4.21e-25: 99.4: 23.85		ATF2_HUMAN (46-352): 2.46e-30: 122: 10.97
+	Hs
		423131 PDIA1_HUMAN (2-103): 7.44e-23: 92.9: 22.22		ATF2_HUMAN (46-352): 2.46e-30: 122: 10.97