Interactor 1: CP51 (P10614)
Lanosterol 14-alpha demethylase CYP51 (EC 1.14.14.154) (Cytochrome P450 51) (Cytochrome P450-14DM) (Cytochrome P450-LIA1) (CYPLI) (Ergosterol biosynthetic protein 11) (Lanosterol C14-C32 lyase) (Sterol 14-alpha demethylase)
Gene: ERG11

Interactor 2: ERG3 (P32353)
Delta(7)-sterol 5(6)-desaturase ERG3 (EC 1.14.19.20) (C-5 sterol desaturase ERG3) (Ergosterol Delta(5,6) desaturase ERG3) (Ergosterol biosynthetic protein 3) (Sterol-C5-desaturase)
Gene: ERG3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 0.60 0.576

The method score is based on:

Property Details
Experiments 16300994, 18467557
Identification Methods protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005506 - iron ion binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006696 - ergosterol biosynthetic process
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 530
Sc

1 365
+ Sc
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024