HitPredict

Interactor 1: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: MAP1LC3B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	33545068, 29149599, 20562859
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005776 - autophagosome GO:0005829 - cytosol GO:0005874 - microtubule GO:0009267 - cellular response to starvation GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 646 Hs			1 125
+	Hs
		714067 HS71L_HUMAN (2-646): 0: 966: 82.48		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		504756 HSP7C_HUMAN (1-646): 0: 967: 100.00		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		714074 HS71L_HUMAN (2-646): 0: 966: 82.48		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		503785 HSP7C_HUMAN (1-646): 0: 967: 100.00		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		713934 HS71L_HUMAN (2-646): 0: 966: 82.48		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		305925 HSP7C_HUMAN (1-646): 0: 967: 100.00		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		305992 HS71L_HUMAN (2-646): 0: 966: 82.48		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		564178 HSP76_HUMAN (6-646): 0: 955: 77.54		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		504734 HSP7C_HUMAN (1-646): 0: 967: 100.00		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		714070 HS71L_HUMAN (2-646): 0: 966: 82.48		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		564184 HSP76_HUMAN (6-646): 0: 955: 77.54		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		483769 HS71A_HUMAN (1-646): 0: 948: 84.37		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		564050 HSP76_HUMAN (6-646): 0: 955: 77.54		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		305951 HSP76_HUMAN (6-646): 0: 955: 77.54		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		564180 HSP76_HUMAN (6-646): 0: 955: 77.54		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		871784 HSP72_HUMAN (2-646): 0: 940: 85.47		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50