Protein: STA5A
Signal transducer and activator of transcription 5A

Gene: STA5A, STAT5A
Organism: Homo sapiens
Interactions: 113
UniProt ID: P42229

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

362915

EGFR
Epidermal growth factor receptor

6

20

Small-scale

0.946

High

838347

STA5B
Signal transducer and activator of transcription 5B

5

16

Small-scale

0.922

High

253320

JAK2
Tyrosine-protein kinase JAK2

4

20

Small-scale

0.888

High

838343

CRKL
Crk-like protein

3

4

Small-scale

0.870

High

619211

EPOR
Erythropoietin receptor

3

20

Small-scale

0.861

High

838365

ERBB4
Receptor tyrosine-protein kinase erbB-4

3

20

Small-scale

0.827

High

252333

TLR2
Toll-like receptor 2

2

2

High-throughput

0.811

High

838354

PTN11
Tyrosine-protein phosphatase non-receptor type 11

2

17

Small-scale

0.789

High

838355

BTK
Tyrosine-protein kinase BTK

1

16

Small-scale

0.761

High

838348

JAK3
Tyrosine-protein kinase JAK3

2

20

Small-scale

0.757

High

611023

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

17

Small-scale

0.757

High

838391

CISH
Cytokine-inducible SH2-containing protein

2

20

Small-scale

0.754

High

658651

JAK1
Tyrosine-protein kinase JAK1

1

20

Small-scale

0.740

High

838340

STA5A
Signal transducer and activator of transcription 5A

1

16

High-throughput

0.698

High

651203

CBL
E3 ubiquitin-protein ligase CBL

4

9

Small-scale

0.680

High

470903

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

3

2

High-throughput

0.675

High

539132

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

3

1

High-throughput

0.675

High

838356

EP300
Histone acetyltransferase p300

3

13

Small-scale

0.669

High

362196

ABL1
Tyrosine-protein kinase ABL1

1

15

Small-scale

0.666

High

575816

IL2RB
Interleukin-2 receptor subunit beta

3

20

Small-scale

0.651

High

132831

ODPX
Pyruvate dehydrogenase protein X component, mitochondrial

2

3

High-throughput

0.628

High

838363

PDK2
[Pyruvate dehydrogenase

2

2

High-throughput

0.628

High

838374

KLHL7
Kelch-like protein 7

2

1

High-throughput

0.628

High

703475

MK01
Mitogen-activated protein kinase 1

2

5

Small-scale

0.624

High

395638

ESR1
Estrogen receptor

2

20

Small-scale

0.621

High

155155

SOCS7
Suppressor of cytokine signaling 7

1

18

Small-scale

0.618

High

484073

PGFRB
Platelet-derived growth factor receptor beta

1

13

Small-scale

0.618

High

532053

KIT
Mast/stem cell growth factor receptor Kit

1

13

Small-scale

0.618

High

599175

IL7RA
Interleukin-7 receptor subunit alpha

1

2

High-throughput

0.618

High

641136

FGFR2
Fibroblast growth factor receptor 2

1

19

Small-scale

0.618

High

711269

SHC1
SHC-transforming protein 1

1

10

Small-scale

0.618

High

714586

TYK2
Non-receptor tyrosine-protein kinase TYK2

1

20

Small-scale

0.618

High

827690

STAT3
Signal transducer and activator of transcription 3

1

16

Small-scale

0.618

High

838009

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

16

Small-scale

0.618

High

838371

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.618

High

838379

OLIG1
Oligodendrocyte transcription factor 1

2

2

High-throughput

0.594

High

789422

PPARG
Peroxisome proliferator-activated receptor gamma

2

20

Small-scale

0.584

High

798800

BRCA1
Breast cancer type 1 susceptibility protein

2

8

Small-scale

0.584

High

522389

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

2

3

High-throughput

0.574

High

838364

PDK3
[Pyruvate dehydrogenase

2

2

High-throughput

0.574

High

838358

NMI
N-myc-interactor

1

6

Small-scale

0.573

High

838373

CARM1
Histone-arginine methyltransferase CARM1

1

4

Small-scale

0.561

High

838387

ANM1
Protein arginine N-methyltransferase 1

1

4

Small-scale

0.561

High

389121

FINC
Fibronectin

1

1

High-throughput

0.555

High

439675

INSR
Insulin receptor

1

14

Small-scale

0.553

High

838384

HTF4
Transcription factor 12

1

0

High-throughput

0.549

High

359608

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

1

High-throughput

0.541

High

794397

RBMX
RNA-binding motif protein, X chromosome

1

2

High-throughput

0.541

High

838341

MAGAC
Melanoma-associated antigen 12

1

2

High-throughput

0.541

High

838380

ZN596
Zinc finger protein 596

1

2

High-throughput

0.541

High

220478

RNF13
E3 ubiquitin-protein ligase RNF13

1

2

High-throughput

0.536

High

838366

SF3A1
Splicing factor 3A subunit 1

1

1

High-throughput

0.536

High

838375

SPICE
Spindle and centriole-associated protein 1

1

1

High-throughput

0.536

High

838388

GDF15
Growth/differentiation factor 15

1

1

High-throughput

0.536

High

838395

DDX20
Probable ATP-dependent RNA helicase DDX20

1

1

High-throughput

0.536

High

838369

TET2
Methylcytosine dioxygenase TET2

1

0

High-throughput

0.529

High

838352

RT06
Small ribosomal subunit protein bS6m

2

1

High-throughput

0.526

High

838390

PRDC1
Phosphoribosyltransferase domain-containing protein 1

1

0

High-throughput

0.518

High

838385

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

3

Small-scale

0.515

High

838394

STAP2
Signal-transducing adaptor protein 2

1

1

Small-scale

0.515

High

334386

SYFM
Phenylalanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

838389

ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C

1

0

High-throughput

0.513

High

838392

ADDG
Gamma-adducin

1

0

High-throughput

0.513

High

838349

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

2

High-throughput

0.508

High

838381

ESR2
Estrogen receptor beta

1

19

Small-scale

0.501

High

838398

ICAM5
Intercellular adhesion molecule 5

1

4

High-throughput

0.489

High

838383

FBXW7
F-box/WD repeat-containing protein 7

1

4

Small-scale

0.481

High

838386

EPAS1
Endothelial PAS domain-containing protein 1

1

6

High-throughput

0.481

High

378614

IL2RA
Interleukin-2 receptor subunit alpha

1

2

Small-scale

0.479

High

442894

PRGR
Progesterone receptor

1

17

Small-scale

0.479

High

519346

MYB
Transcriptional activator Myb

1

1

Small-scale

0.479

High

533896

IRF1
Interferon regulatory factor 1

1

20

Small-scale

0.479

High

576185

PO2F1
POU domain, class 2, transcription factor 1

1

5

Small-scale

0.479

High

626114

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

10

Small-scale

0.479

High

635829

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

1

Small-scale

0.479

High

664666

CCND1
G1/S-specific cyclin-D1

1

5

Small-scale

0.479

High

718772

CCND2
G1/S-specific cyclin-D2

1

5

Small-scale

0.479

High

832669

BCL6
B-cell lymphoma 6 protein

1

2

Small-scale

0.479

High

838342

CBX5
Chromobox protein homolog 5

1

1

Small-scale

0.479

High

838344

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

6

High-throughput

0.479

High

838345

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

5

Small-scale

0.479

High

838353

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.479

High

838357

CBLB
E3 ubiquitin-protein ligase CBL-B

1

3

Small-scale

0.479

High

838359

SQSTM
Sequestosome-1

1

1

Small-scale

0.479

High

838360

HDAC1
Histone deacetylase 1

1

11

Small-scale

0.479

High

838361

RUNX2
Runt-related transcription factor 2

1

1

Small-scale

0.479

High

838367

NCOA1
Nuclear receptor coactivator 1

1

10

Small-scale

0.479

High

838393

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

838396

LEF1
Lymphoid enhancer-binding factor 1

1

1

Small-scale

0.479

High

838397

TBX21
T-box transcription factor TBX21

1

6

Small-scale

0.479

High

838399

R3HD2
R3H domain-containing protein 2

1

5

High-throughput

0.479

High

548318

CP2C9
Cytochrome P450 2C9

1

0

High-throughput

0.460

High

838350

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.460

High

838376

AQP11
Aquaporin-11

1

0

High-throughput

0.460

High

424330

IL5
Interleukin-5

1

0

Small-scale

0.458

High

582055

IL9
Interleukin-9

1

0

Small-scale

0.458

High

838346

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.458

High

838377

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

299096

FLOT1
Flotillin-1

1

5

High-throughput

0.457

High

838362

FLOT2
Flotillin-2

1

5

High-throughput

0.457

High

838378

ANGL6
Angiopoietin-related protein 6

1

4

High-throughput

0.457

High

748673

IL3RB
Cytokine receptor common subunit beta

1

19

Small-scale

0.445

High

838368

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.445

High

838382

CBP
CREB-binding protein

1

14

Small-scale

0.445

High

76098

B4DET5
cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121

1

2

High-throughput

0.439

High

838370

TXD11
Thioredoxin domain-containing protein 11

1

2

High-throughput

0.439

High

838351

KRT83
Keratin, type II cuticular Hb3

1

0

High-throughput

0.426

High

81645

B5MCU0
R3H domain containing 2

1

5

High-throughput

0.407

High

317710

NOL4
Nucleolar protein 4

1

0

High-throughput

0.279

Low

838372

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

0

High-throughput

0.279

Low

438973

UD2B4
UDP-glucuronosyltransferase 2B4

1

0

High-throughput

0.251

Low

596463

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

Small-scale

0.238

Low


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Last updated: 11Aug2025