HitPredict

Interactor 1: MBL2 (P11226)
Mannose-binding protein C (MBP-C) (Collectin-1) (MBP1) (Mannan-binding protein) (Mannose-binding lectin)
Gene: MBL2

Interactor 2: MBL2 (P11226)
Mannose-binding protein C (MBP-C) (Collectin-1) (MBP1) (Mannan-binding protein) (Mannose-binding lectin)
Gene: MBL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.922

The method score is based on:

Property Details
Experiments 25579818, 21106539, 21383675, 27104295, 22607836
Identification Methods comigration in sds page, comigration in non denaturing gel electrophoresis, ion exchange chromatography
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Collagen~Collagen, Lectin_C~Lectin_C
Common GO terms GO:0001867 - complement activation, lectin pathway
GO:0002752 - cell surface pattern recognition receptor signaling pathway
GO:0005102 - signaling receptor binding
GO:0005537 - D-mannose binding
GO:0005576 - extracellular region
and 21 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 248
Hs

1 248
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024