Interactor 1: BCR (P11274)
Breakpoint cluster region protein (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-26)
Gene: BCR

Interactor 2: SOS1 (Q07889)
Son of sevenless homolog 1 (SOS-1)
Gene: SOS1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 8112292, 7529874
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~RhoGEF, RasGEF_N~RhoGEF, RhoGEF~RhoGEF
Common GO terms GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1271
Hs

1 1333
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024