HitPredict

Interactor 1: BCR (P11274)
Breakpoint cluster region protein (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-26)
Gene: BCR

Interactor 2: GRAP (Q13588)
GRB2-related adapter protein
Gene: GRAP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	8995379
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	C2~SH2, RhoGEF~SH3_1
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1271 Hs			1 217
+	Hs
		506565 BCR_HUMAN (1-1271): 0: 1005: 100.00		GRB2_HUMAN (1-216): 4.15e-69: 212: 59.72
+	Hs
		337325 BCR_HUMAN (1-1271): 0: 1005: 100.00		ABL1_HUMAN (3-180): 4.01e-52: 182: 31.69
+	Hs
		442768 BCR_HUMAN (1-1271): 0: 1005: 100.00		HCK_HUMAN (4-158): 6.34e-52: 176: 32.74
+	Mm
		1141138 BCR_MOUSE (1-1271): 0: 941: 93.79		GRB2_MOUSE (1-216): 3.23e-69: 212: 59.72
+	Hs
		506538 BCR_HUMAN (1-1271): 0: 1005: 100.00		FRK_HUMAN (3-204): 1.2e-34: 130: 29.68
+	Hs
		275167 BCR_HUMAN (1-1271): 0: 1005: 100.00		GRAP2_HUMAN (3-55): 1.64e-11: 64.4: 33.96
+	Hs
		337453 ABR_HUMAN (419-1271): 0: 567: 66.47		ABL1_HUMAN (3-180): 4.01e-52: 182: 31.69
+	Hs
		924658 FGD6_HUMAN (93-969): 1.47e-86: 311: 14.15		GRB2_HUMAN (1-216): 4.15e-69: 212: 59.72
+	Hs
		924525 ARHG5_HUMAN (95-862): 8.55e-82: 297: 14.49		GRB2_HUMAN (1-216): 4.15e-69: 212: 59.72
+	Mm
		654982 VAV_MOUSE (393-1106): 2.14e-78: 279: 11.78		GRB2_MOUSE (1-216): 3.23e-69: 212: 59.72
+	Hs
		924777 Q96D37_HUMAN (393-1092): 1.17e-77: 275: 12.29		GRB2_HUMAN (1-216): 4.15e-69: 212: 59.72
+	Hs
		337333 VAV_HUMAN (393-1092): 5.12e-77: 275: 12.29		ABL1_HUMAN (3-180): 4.01e-52: 182: 31.69
+	Hs
		433726 ARHG5_HUMAN (95-862): 8.55e-82: 297: 14.49		LYN_HUMAN (4-204): 4.34e-36: 134: 25.58
+	Hs
		411673 FGD1_HUMAN (162-971): 1.22e-77: 279: 13.57		LCK_HUMAN (4-204): 1.02e-41: 149: 26.98
+	Hs
		411580 VAV_HUMAN (393-1092): 5.12e-77: 275: 12.29		LCK_HUMAN (4-204): 1.02e-41: 149: 26.98
+	Hs
		433781 ITSN1_HUMAN (74-927): 1.53e-78: 287: 13.61		LYN_HUMAN (4-204): 4.34e-36: 134: 25.58
+	Hs
		1078876 PREX1_HUMAN (447-1058): 2.05e-83: 302: 15.70		ITSN1_HUMAN (50-215): 1.73e-13: 70.7: 12.36
+	Hs
		1078919 ITSN1_HUMAN (74-927): 1.53e-78: 287: 13.61		ITSN2_HUMAN (106-215): 4.33e-14: 72.7: 24.11
+	Hs
		1078828 ITSN1_HUMAN (74-927): 1.53e-78: 287: 13.61		ITSN1_HUMAN (50-215): 1.73e-13: 70.7: 12.36
+	Hs
		411981 VAV_HUMAN (393-1092): 5.12e-77: 275: 12.29		FYN_HUMAN (154-215): 1.46e-12: 67.7: 31.25