HitPredict

Interactor 1: ERG (P11308)
Transcriptional regulator ERG (Transforming protein ERG)
Gene: ERG

Interactor 2: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)
Gene: PRKDC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.664

The method score is based on:

Property Details
Experiments 21575865, 24591637
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, chromatin immunoprecipitation assay
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006468 - protein phosphorylation
and 1 others

more...
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 479
Hs

1 4128
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024