Interactor 1: TOP1 (P11387)
DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I)
Gene: TOP1

Interactor 2: H12 (P16403)
Histone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1)
Gene: H1-2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.51 0.55 0.530

The method score is based on:

Property Details
Experiments 15848144
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003690 - double-stranded DNA binding
GO:0003723 - RNA binding
GO:0005634 - nucleus
Homologous interactions 0

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Last updated: 15 Jul 2024