HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	21145461, 19214193
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 334
+	Hs
		137925 UBC_HUMAN (1-685): 0: 857: 100.00		PSDE_HUMAN (50-331): 1.68e-79: 246: 31.51
+	Hs
		187869 UBC_HUMAN (1-685): 0: 857: 100.00		EIF3H_HUMAN (52-320): 2.18e-66: 214: 18.57
+	Hs
		507700 UBC_HUMAN (1-685): 0: 857: 100.00		PSMD7_HUMAN (52-325): 1.07e-66: 214: 14.79
+	Hs
		131303 UBC_HUMAN (1-685): 0: 857: 100.00		EIF3F_HUMAN (44-328): 3.26e-64: 208: 14.48
+	Hs
		507662 UBC_HUMAN (1-685): 0: 857: 100.00		BRCC3_HUMAN (56-203): 4.63e-43: 152: 21.23
+	Rn
		93354 UBC_RAT (1-637): 0: 779: 98.90		D4AEH3_RAT (52-325): 6.38e-62: 201: 14.44
+	Hs
		508118 UBC_HUMAN (1-685): 0: 857: 100.00		MYSM1_HUMAN (39-172): 3.52e-29: 119: 23.29
+	At
		1167735 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		CSN5A_ARATH (1-334): 5.45e-121: 354: 65.69
+	Sc
		509607 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		RPN11_YEAST (39-333): 9.62e-75: 234: 29.14
+	Sc
		509773 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		CSN5_YEAST (22-299): 9.36e-57: 191: 29.51
+	Sc
		509748 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		RPN8_YEAST (53-326): 4.47e-57: 190: 16.61
+	At
		1168114 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		PSDE_ARATH (41-331): 1.05e-80: 249: 31.56
+	Mm
		205602 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		CSN5_MOUSE (1-334): 1.02e-130: 378: 99.40
+	At
		1167911 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		PSD7B_ARATH (46-326): 2.02e-68: 218: 15.17
+	At
		200893 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		PSD7A_ARATH (46-326): 8.58e-69: 218: 14.48
+	At
		1167907 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		EIF3H_ARATH (39-314): 3.36e-59: 195: 17.90
+	Hs
		138057 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		PSDE_HUMAN (50-331): 1.68e-79: 246: 31.51
+	Sp
		509848 UBI4P_SCHPO (1-230): 5.27e-90: 287: 95.22		SST2_SCHPO (74-191): 8.98e-24: 103: 22.95
+	Mm
		204963 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		PSDE_MOUSE (50-331): 1.68e-79: 246: 31.51
+	Mm
		508960 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		PSMD7_MOUSE (52-325): 8e-67: 214: 14.79