HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: UBAC1 (Q9BSL1)
Ubiquitin-associated domain-containing protein 1 (UBA domain-containing protein 1) (Glialblastoma cell differentiation-related protein 1) (Kip1 ubiquitination-promoting complex protein 2)
Gene: UBAC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.725

Property	Details
Experiments	32296183, 28190767, 31494268, 38803224, unassigned1304, unassigned3799
Identification Methods	two hybrid, pull down, unspecified method, validated two hybrid, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016567 - protein ubiquitination GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 405
+	Hs
		508376 UBC_HUMAN (1-685): 0: 857: 100.00		UBP13_HUMAN (168-335): 1.26e-43: 164: 24.59
+	Hs
		507656 UBC_HUMAN (1-685): 0: 857: 100.00		UBP5_HUMAN (168-326): 1.37e-40: 155: 21.62
+	Hs
		507861 UBC_HUMAN (1-685): 0: 857: 100.00		UBXN1_HUMAN (191-276): 1.8e-20: 92.6: 37.50
+	Rn
		92895 UBC_RAT (1-637): 0: 779: 98.90		D3ZDI9_RAT (168-335): 3e-41: 157: 20.22
+	Rn
		93126 UBC_RAT (1-637): 0: 779: 98.90		D3ZVQ0_RAT (168-326): 2.43e-41: 157: 21.62
+	Hs
		987187 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		UBAC1_HUMAN (1-405): 0: 579: 100.00
+	Mm
		509200 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		UBAC1_MOUSE (1-405): 0: 574: 88.75
+	Hs
		507349 UBB_HUMAN (1-77): 1.15e-26: 110: 98.70		UBAC1_HUMAN (1-405): 0: 579: 100.00
+	Sc
		509516 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		UBP14_YEAST (170-328): 2.89e-16: 82.9: 18.13
+	At
		1167722 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		UBP14_ARATH (168-328): 5.47e-33: 133: 20.99
+	Hs
		853454 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		UBP5_HUMAN (168-326): 1.37e-40: 155: 21.62
+	Mm
		509075 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		UBP13_MOUSE (168-335): 5.29e-44: 165: 20.77
+	Mm
		508993 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		UBP5_MOUSE (168-326): 1.12e-40: 155: 21.62
+	Hs
		507109 UBB_HUMAN (1-77): 1.15e-26: 110: 98.70		UBP5_HUMAN (168-326): 1.37e-40: 155: 21.62
+	Mm
		940742 ISG15_MOUSE (456-608): 3.93e-25: 104: 33.12		UBP5_MOUSE (168-326): 1.12e-40: 155: 21.62
+	Mm
		509226 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		UBXN1_MOUSE (191-276): 2.17e-19: 89.5: 36.46