HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: RNF38 (Q9H0F5)
E3 ubiquitin-protein ligase RNF38 (EC 2.3.2.27) (RING finger protein 38) (RING-type E3 ubiquitin transferase RNF38)
Gene: RNF38

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.692

Property	Details
Experiments	25801170
Identification Methods	pull down, enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016567 - protein ubiquitination
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 515
+	Hs
		508165 UBC_HUMAN (1-685): 0: 857: 100.00		RN111_HUMAN (2-508): 5.35e-51: 189: 17.74
+	Hs
		508544 UBC_HUMAN (1-685): 0: 857: 100.00		RN126_HUMAN (253-514): 1.59e-41: 152: 19.29
+	Hs
		508893 UBC_HUMAN (1-685): 0: 857: 100.00		RN115_HUMAN (260-515): 1.14e-39: 147: 17.36
+	Hs
		508714 UBC_HUMAN (1-685): 0: 857: 100.00		RNF12_HUMAN (13-508): 1.9e-33: 136: 16.41
+	Hs
		508170 UBC_HUMAN (1-685): 0: 857: 100.00		ARK2C_HUMAN (158-510): 1.72e-30: 123: 19.67
+	Hs
		508292 UBC_HUMAN (1-685): 0: 857: 100.00		ZNRF1_HUMAN (290-501): 1.63e-31: 123: 15.25
+	Hs
		220468 UBC_HUMAN (1-685): 0: 857: 100.00		RNF13_HUMAN (440-509): 6.51e-27: 114: 36.62
+	At
		1167755 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		RNG1L_ARATH (316-515): 1.4e-34: 134: 19.54
+	At
		1020702 UBQ3_ARATH (457-685): 4e-89: 282: 95.63		ATL1_ARATH (436-508): 7.21e-28: 116: 33.33
+	Mm
		509240 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		RN111_MOUSE (2-508): 5.23e-51: 189: 18.31
+	Hs
		987237 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		RNF12_HUMAN (13-508): 1.9e-33: 136: 16.41
+	Mm
		509263 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		RN115_MOUSE (260-515): 3.53e-42: 154: 17.36
+	Mm
		509216 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		RN126_MOUSE (253-514): 1.96e-39: 147: 17.38
+	Mm
		509320 UBC_MOUSE (1-108): 2.12e-30: 129: 90.74		RNF12_MOUSE (65-510): 9.24e-34: 136: 15.43
+	Hs
		507354 UBB_HUMAN (1-77): 1.15e-26: 110: 98.70		RN126_HUMAN (253-514): 1.59e-41: 152: 19.29
+	Hs
		507283 UBB_HUMAN (1-77): 1.15e-26: 110: 98.70		ZNRF1_HUMAN (290-501): 1.63e-31: 123: 15.25
+	Zm
		82463 B6SKC9_MAIZE (376-527): 1.65e-17: 88.2: 27.56		C0P544_MAIZE (369-507): 7.01e-30: 118: 23.40