HitPredict

Interactor 1: CDC24 (P11433)
Cell division control protein 24 (Calcium regulatory protein)
Gene: CDC24

Interactor 2: RSR1 (P13856)
Ras-related protein RSR1 (EC 3.6.5.2)
Gene: RSR1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	1.00	0.962

Property	Details
Experiments	11489916, 9114012, 7822288, 14988726, 32327559, 25416945, 22117027
Identification Methods	two hybrid, affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGEF
Common GO terms	GO:0000131 - incipient cellular bud site GO:0005935 - cellular bud neck
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 854 Sc			1 272
+	Sc
		350758 CDC24_YEAST (1-854): 0: 591: 100.00		RAS1_YEAST (1-208): 4.5e-45: 155: 49.04
+	Hs
		914091 ITSN1_HUMAN (103-591): 3.27e-89: 312: 17.91		RB11A_HUMAN (4-208): 1.01e-76: 233: 26.21
+	Hs
		895058 TIAM1_HUMAN (57-781): 3.01e-85: 300: 16.47		RAB2A_HUMAN (4-188): 9.1e-80: 241: 32.80
+	Hs
		279852 TRIO_HUMAN (173-775): 9.94e-67: 245: 14.65		RB11A_HUMAN (4-208): 1.01e-76: 233: 26.21
+	Dm
		218242 O44381_DROME (251-777): 7.16e-76: 272: 17.58		O96692_DROME (1-165): 1.64e-43: 147: 50.30
+	Dm
		55331 A1ZAN6_DROME (251-777): 7.3e-76: 272: 17.58		O96692_DROME (1-165): 1.64e-43: 147: 50.30
+	Dm
		71594 B3DN64_DROME (261-485): 7.32e-13: 74.7: 28.38		RALA_DROME (4-183): 8.15e-44: 149: 41.67
+	Dm
		1229130 Q8MSP7_DROME (261-485): 7.26e-13: 74.7: 28.38		Q962I2_DROME (4-165): 1.09e-43: 148: 45.06