HitPredict

Interactor 1: UBL4A (P11441)
Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
Gene: UBL4A

Interactor 2: RN126 (Q9BV68)
E3 ubiquitin-protein ligase RNF126 (EC 2.3.2.27) (RING finger protein 126)
Gene: RNF126

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	27193484, 23246001
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_2, ubiquitin~zinc_ribbon_9
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 157 Hs			1 311
+	Hs
		1237129 UBL4B_HUMAN (1-146): 2.55e-47: 153: 44.52		RN126_HUMAN (1-311): 3.19e-81: 250: 100.00
+	Hs
		475173 UBB_HUMAN (1-76): 1.43e-29: 109: 39.47		RN126_HUMAN (1-311): 3.19e-81: 250: 100.00
+	Hs
		476301 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		RN126_HUMAN (1-311): 3.19e-81: 250: 100.00
+	Mm
		476947 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		RN126_MOUSE (1-311): 4.83e-79: 244: 93.61
+	Mm
		476994 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		RN115_MOUSE (10-291): 2.76e-59: 193: 44.52
+	Hs
		476628 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		RN115_HUMAN (10-307): 1.16e-57: 189: 43.00
+	At
		1091813 UBQ3_ARATH (1-77): 2.19e-28: 107: 37.66		RNG1L_ARATH (2-304): 3.13e-49: 168: 24.35
+	At
		1210477 UBQ10_ARATH (1-76): 2.3e-27: 107: 38.16		Q9FM98_ARATH (8-310): 3.36e-41: 149: 21.74
+	At
		477669 UBQ11_ARATH (1-76): 5.64e-29: 107: 38.16		Q9FM98_ARATH (8-310): 3.36e-41: 149: 21.74
+	Hs
		924057 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		GOLI_HUMAN (205-311): 1.76e-29: 118: 29.57
+	Hs
		924199 RS27A_HUMAN (1-123): 2.9e-40: 134: 28.46		RN181_HUMAN (193-283): 1.04e-29: 112: 34.07
+	Hs
		476347 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		RNF38_HUMAN (55-272): 8.94e-35: 133: 25.11
+	Hs
		475946 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		ARK2C_HUMAN (67-281): 1.9e-31: 122: 19.48
+	Mm
		476987 UBC_MOUSE (1-102): 1.77e-28: 111: 31.13		RN181_MOUSE (177-283): 5.73e-32: 118: 32.14
+	Hs
		475090 UBB_HUMAN (1-76): 1.43e-29: 109: 39.47		GOLI_HUMAN (205-311): 1.76e-29: 118: 29.57
+	Hs
		476073 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		PJA1_HUMAN (38-276): 2.32e-29: 119: 20.33
+	Hs
		476007 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		GOLI_HUMAN (205-311): 1.76e-29: 118: 29.57
+	Hs
		475516 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		TTC3_HUMAN (22-300): 1.94e-27: 114: 15.16
+	Hs
		475216 UBB_HUMAN (1-76): 1.43e-29: 109: 39.47		RN181_HUMAN (193-283): 1.04e-29: 112: 34.07
+	Hs
		476491 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		RN181_HUMAN (193-283): 1.04e-29: 112: 34.07