HitPredict

Interactor 1: STAM2 (O75886)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: UBB (P0CG47)
Polyubiquitin-B [Cleaved into: Ubiquitin]
Gene: UBB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH3_1~ubiquitin, UIM~ubiquitin, VHS~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 229
+	Hs
		296426 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		UBC_HUMAN (1-228): 7.54e-92: 285: 100.00
+	Hs
		508369 STAM1_HUMAN (1-510): 4.16e-112: 345: 54.88		UBC_HUMAN (1-228): 7.54e-92: 285: 100.00
+	Mm
		313050 STAM2_MOUSE (1-525): 1.57e-132: 396: 85.14		UBC_MOUSE (1-181): 8.42e-63: 209: 96.13
+	Hs
		296483 STAM2_HUMAN (1-525): 1.05e-141: 420: 100.00		RS27A_HUMAN (153-228): 1.77e-44: 147: 100.00
+	Hs
		508173 TM1L2_HUMAN (1-466): 1.87e-87: 280: 17.19		UBC_HUMAN (1-228): 7.54e-92: 285: 100.00
+	Mm
		509025 STAM1_MOUSE (1-513): 2.67e-115: 353: 53.96		UBC_MOUSE (1-181): 8.42e-63: 209: 96.13
+	Rn
		81583 B5DF55_RAT (1-513): 4.44e-113: 347: 54.25		UBC_RAT (1-181): 3.75e-62: 209: 96.13
+	Hs
		256434 TOM1_HUMAN (1-444): 8.1e-81: 262: 17.68		UBC_HUMAN (1-228): 7.54e-92: 285: 100.00
+	Hs
		290232 TM1L1_HUMAN (6-494): 1.97e-65: 221: 15.62		UBC_HUMAN (1-228): 7.54e-92: 285: 100.00
+	Hs
		507412 GGA1_HUMAN (2-516): 2.51e-62: 217: 14.50		UBB_HUMAN (1-229): 2.65e-99: 289: 100.00
+	Hs
		508803 GGA1_HUMAN (2-516): 2.51e-62: 217: 14.50		UBC_HUMAN (1-228): 7.54e-92: 285: 100.00
+	Bt
		509943 Q58CQ6_BOVIN (2-422): 8.25e-64: 216: 13.43		UBC_BOVIN (1-228): 1.42e-91: 284: 99.12
+	Ce
		144704 STAM1_CAEEL (4-395): 1.48e-65: 221: 27.03		UBIQ1_CAEEL (1-228): 5.62e-88: 278: 98.25
+	Hs
		987143 STAM1_HUMAN (1-510): 4.16e-112: 345: 54.88		RS27A_HUMAN (153-228): 1.77e-44: 147: 100.00
+	Mm
		509080 TM1L2_MOUSE (1-466): 3.32e-87: 279: 17.79		UBC_MOUSE (1-181): 8.42e-63: 209: 96.13
+	Sc
		509585 VPS27_YEAST (1-488): 9.24e-59: 207: 16.02		UBI4P_YEAST (1-228): 3.4e-91: 274: 96.05
+	Mm
		312915 TOM1_MOUSE (1-465): 1.7e-83: 269: 17.10		UBC_MOUSE (1-181): 8.42e-63: 209: 96.13
+	Mm
		509190 GGA1_MOUSE (2-516): 3.94e-64: 221: 13.74		UBC_MOUSE (1-181): 8.42e-63: 209: 96.13
+	Mm
		509153 GGA3_MOUSE (1-513): 1.96e-58: 208: 15.33		UBC_MOUSE (1-181): 8.42e-63: 209: 96.13
+	Rn
		591440 SPTN1_RAT (103-481): 1.05e-55: 204: 14.35		UBC_RAT (1-181): 3.75e-62: 209: 96.13