Interactor 1: VDR (P11473)
Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor) (Nuclear receptor subfamily 1 group I member 1)
Gene: VDR
Interactor 2: RXRG (P48443)
Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma)
Gene: RXRG
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.83 | 1.00 | 0.916 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 15919723, 15604093, unassigned1304, 20211142 |
| Identification Methods | two hybrid, two hybrid prey pooling approach, two hybrid array, mammalian protein protein interaction trap, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Hormone_recep~Hormone_recep, Hormone_recep~zf-C4, zf-C4~zf-C4 |
| Common GO terms | GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0004879 - nuclear receptor activity GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding and 3 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
