Protein: UBP38
Ubiquitin carboxyl-terminal hydrolase 38 (EC 3.4.19.12) (Deubiquitinating enzyme 38) (HP43.8KD) (Ubiquitin thioesterase 38) (Ubiquitin-specific-processing protease 38)

Gene: UBP38, USP38
Organism: Homo sapiens
Interactions: 37
UniProt ID: Q8NB14

Gene Ontology (top 5):
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

595822

H13
Histone H1.3

3

2

High-throughput

0.667

High

937298

DSRAD
Double-stranded RNA-specific adenosine deaminase

3

6

High-throughput

0.667

High

508284

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

20

High-throughput

0.647

High

987118

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

20

Small-scale

0.618

High

1332951

UBP38
Ubiquitin carboxyl-terminal hydrolase 38

1

15

Small-scale

0.618

High

1332954

FBXW7
F-box/WD repeat-containing protein 7

1

11

Small-scale

0.618

High

389749

FETUA
Alpha-2-HS-glycoprotein

3

1

High-throughput

0.609

High

65843

HMX3
Homeobox protein HMX3

2

4

Small-scale

0.584

High

1109904

HDAC1
Histone deacetylase 1

1

14

Small-scale

0.578

High

754914

H2B1B
Histone H2B type 1-B

1

15

Small-scale

0.561

High

415731

HSPB1
Heat shock protein beta-1

1

3

High-throughput

0.536

High

868739

LEG7
Galectin-7

1

5

High-throughput

0.536

High

954717

SEM1
26S proteasome complex subunit SEM1

1

1

Small-scale

0.536

High

334351

TRI16
Tripartite motif-containing protein 16

1

20

High-throughput

0.515

High

603313

KPCA
Protein kinase C alpha type

1

7

High-throughput

0.515

High

966622

1433G
14-3-3 protein gamma

1

20

High-throughput

0.515

High

1139770

SETB1
Histone-lysine N-methyltransferase SETDB1

1

5

High-throughput

0.515

High

1332952

LMO3
LIM domain only protein 3

1

3

High-throughput

0.515

High

1332953

KAT5
Histone acetyltransferase KAT5

1

1

High-throughput

0.515

High

612707

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.513

High

673913

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.513

High

913664

VAV2
Guanine nucleotide exchange factor VAV2

1

9

High-throughput

0.508

High

132748

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

12

Small-scale

0.479

High

163647

GNB5
Guanine nucleotide-binding protein subunit beta-5

1

3

High-throughput

0.479

High

188695

BIRC5
Baculoviral IAP repeat-containing protein 5

1

20

Small-scale

0.479

High

246767

KDM1A
Lysine-specific histone demethylase 1A

1

2

Small-scale

0.479

High

407319

K2C6B
Keratin, type II cytoskeletal 6B

1

9

Small-scale

0.479

High

553238

KCRB
Creatine kinase B-type

1

1

Small-scale

0.479

High

868212

SYQ
Glutamine--tRNA ligase

1

1

Small-scale

0.479

High

881246

FAS
Fatty acid synthase

1

6

Small-scale

0.479

High

998552

H31
Histone H3.1

1

3

Small-scale

0.479

High

1128241

MCM6
DNA replication licensing factor MCM6

1

11

Small-scale

0.479

High

1332955

KDM5B
Lysine-specific demethylase 5B

1

4

Small-scale

0.479

High

1332956

ZHX2
Zinc fingers and homeoboxes protein 2

1

1

Small-scale

0.479

High

358749

LDHA
L-lactate dehydrogenase A chain

1

0

Small-scale

0.458

High

60665

HMX2
Homeobox protein HMX2

1

9

High-throughput

0.445

High


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Last updated: 11Aug2025