Interactor 1: PYC (P11498)
Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase) (PCB)
Gene: PC
Interactor 2: ACACA (Q13085)
Acetyl-CoA carboxylase 1 (ACC1) (EC 6.4.1.2) (Acetyl-Coenzyme A carboxylase alpha) (ACC-alpha)
Gene: ACACA
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24981860 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Biotin_carb_C~Biotin_carb_C, Biotin_carb_C~Biotin_carb_N, Biotin_carb_C~Biotin_lipoyl, Biotin_carb_C~Carboxyl_trans, Biotin_carb_C~CPSase_L_D2, ACC_central~Biotin_carb_N, Biotin_carb_N~Biotin_carb_N, Biotin_carb_N~Biotin_lipoyl, Biotin_carb_N~CPSase_L_D2, ACC_central~Biotin_lipoyl, Biotin_lipoyl~Biotin_lipoyl, Biotin_lipoyl~Carboxyl_trans, Biotin_lipoyl~CPSase_L_D2, CPSase_L_D2~CPSase_L_D2, Biotin_carb_C~PYC_OADA, Biotin_carb_N~PYC_OADA, Biotin_lipoyl~PYC_OADA |
| Common GO terms | GO:0005524 - ATP binding GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0046872 - metal ion binding |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
 |
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Ec | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
