Protein: UTP15
U3 small nucleolar RNA-associated protein 15 (U3 snoRNA-associated protein 15) (U three protein 15) (U3 protein 15 required for transcription) (t-UTP15)

Gene: UTP15
Organism: Saccharomyces cerevisiae S288C
Interactions: 152
UniProt ID: Q04305

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006364 - rRNA processing
GO:0030490 - maturation of SSU-rRNA

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1045100

UTP5
U3 small nucleolar RNA-associated protein 5

7

16

Small-scale

0.968

High

1046261

UTP4
U3 small nucleolar RNA-associated protein 4

7

18

Small-scale

0.963

High

678452

PWP2
Periodic tryptophan protein 2

7

20

Small-scale

0.962

High

1039844

UTP17
NET1-associated nuclear protein 1

6

17

Small-scale

0.945

High

817625

UTP7
U3 small nucleolar RNA-associated protein 7

4

18

High-throughput

0.900

High

823380

UTP18
U3 small nucleolar RNA-associated protein 18

4

1

High-throughput

0.892

High

1046019

DHR1
Probable ATP-dependent RNA helicase DHR1

4

11

Small-scale

0.873

High

1046258

RRP9
Ribosomal RNA-processing protein 9

3

19

High-throughput

0.861

High

852597

ROK1
ATP-dependent RNA helicase ROK1

2

10

High-throughput

0.789

High

844600

UTP10
U3 small nucleolar RNA-associated protein 10

10

4

Small-scale

0.756

High

864511

MTR4
ATP-dependent RNA helicase DOB1

2

19

Small-scale

0.754

High

798301

ENP1
Essential nuclear protein 1

8

1

Small-scale

0.747

High

1046259

NOC4
Nucleolar complex protein 4

7

6

Small-scale

0.743

High

806567

UTP9
U3 small nucleolar RNA-associated protein 9

8

0

Small-scale

0.721

High

919164

UTP8
U3 small nucleolar RNA-associated protein 8

8

0

Small-scale

0.720

High

1046282

NOP58
Nucleolar protein 58

5

9

Small-scale

0.714

High

917473

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

8

High-throughput

0.691

High

1046246

ERB1
Ribosome biogenesis protein ERB1

1

17

High-throughput

0.691

High

1046251

UTP21
U3 small nucleolar RNA-associated protein 21

4

20

Small-scale

0.686

High

677551

KRR1
KRR1 small subunit processome component

5

0

High-throughput

0.686

High

1036402

UTP6
U3 small nucleolar RNA-associated protein 6

3

2

High-throughput

0.667

High

865163

MPP10
U3 small nucleolar RNA-associated protein MPP10

3

5

Small-scale

0.656

High

1046283

RRP12
Ribosomal RNA-processing protein 12

3

1

High-throughput

0.656

High

1046270

UTP16
U3 small nucleolar RNA-associated protein 16

3

0

High-throughput

0.638

High

632734

DBP4
ATP-dependent RNA helicase HCA4

1

16

High-throughput

0.618

High

682374

SPB4
ATP-dependent rRNA helicase SPB4

1

18

High-throughput

0.618

High

754326

DCA13
Protein SOF1

1

17

High-throughput

0.618

High

802901

DBP8
ATP-dependent RNA helicase DBP8

1

13

High-throughput

0.618

High

874516

RS12
Small ribosomal subunit protein eS12

1

3

High-throughput

0.618

High

918983

PESC
Pescadillo homolog

1

3

High-throughput

0.618

High

1046250

UTP13
U3 small nucleolar RNA-associated protein 13

1

19

High-throughput

0.618

High

1046277

UTP12
U3 small nucleolar RNA-associated protein 12

1

17

High-throughput

0.618

High

1046279

DBP10
ATP-dependent RNA helicase DBP10

1

15

High-throughput

0.618

High

826207

FAF1
Protein FAF1

2

0

Small-scale

0.585

High

923980

CSL4
Exosome complex component CSL4

2

2

High-throughput

0.584

High

924624

NAT10
RNA cytidine acetyltransferase

2

2

High-throughput

0.584

High

1046245

UTP14
U3 small nucleolar RNA-associated protein 14

2

8

High-throughput

0.584

High

1046247

RRP5
rRNA biogenesis protein RRP5

2

13

High-throughput

0.584

High

1046275

RRP6
Exosome complex exonuclease RRP6

2

6

High-throughput

0.584

High

794311

DUG2
Probable di- and tripeptidase DUG2

1

0

High-throughput

0.578

High

747568

RSSA1
Small ribosomal subunit protein uS2A

2

2

High-throughput

0.571

High

1046281

RRP36
rRNA biogenesis protein RRP36

2

0

Small-scale

0.559

High

383886

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.553

High

871120

MTR3
Exosome complex component MTR3

2

0

High-throughput

0.547

High

851014

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.541

High

546182

SSB1
Ribosome-associated molecular chaperone SSB1

1

14

High-throughput

0.536

High

688944

RS5
Small ribosomal subunit protein uS7

1

5

High-throughput

0.536

High

803928

CIC1
Proteasome-interacting protein CIC1

1

6

High-throughput

0.536

High

1046252

MRD1
Multiple RNA-binding domain-containing protein 1

1

3

Small-scale

0.536

High

592490

VATB
V-type proton ATPase subunit B

2

7

High-throughput

0.533

High

740756

SRP40
Suppressor protein SRP40

1

3

High-throughput

0.515

High

816176

DPO5
rDNA transcriptional regulator POL5

1

4

High-throughput

0.515

High

1046262

TSR1
Ribosome biogenesis protein TSR1

1

6

High-throughput

0.515

High

645529

XRN1
5'-3' exoribonuclease 1

1

4

High-throughput

0.500

High

757412

TFC3
Transcription factor tau 138 kDa subunit

1

0

High-throughput

0.493

High

722238

XPO1
Exportin-1

1

13

High-throughput

0.489

High

149946

RS9A
Small ribosomal subunit protein uS4A

1

6

High-throughput

0.479

High

435347

RS3
Small ribosomal subunit protein uS3

1

5

High-throughput

0.479

High

436163

RS13
Small ribosomal subunit protein uS15

1

4

High-throughput

0.479

High

512639

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.479

High

513208

RS8A
Small ribosomal subunit protein eS8A

1

4

High-throughput

0.479

High

585364

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

7

High-throughput

0.479

High

647213

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

2

High-throughput

0.479

High

671093

SIS1
Protein SIS1

1

10

High-throughput

0.479

High

689649

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.479

High

735150

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

747044

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

6

High-throughput

0.479

High

753576

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.479

High

782100

RL1D1
Ribosome biogenesis protein UTP30

1

6

High-throughput

0.479

High

804745

RRP4
Exosome complex component RRP4

1

10

High-throughput

0.479

High

808303

RRP8
25S rRNA

1

2

High-throughput

0.479

High

863132

RRP41
Exosome complex component SKI6

1

15

High-throughput

0.479

High

864956

NOP9
Nucleolar protein 9

1

1

Small-scale

0.479

High

871049

NOL10
Ribosome biogenesis protein ENP2

1

2

High-throughput

0.479

High

918816

UTP22
U3 small nucleolar RNA-associated protein 22

1

2

High-throughput

0.479

High

918888

RRP46
Exosome complex component RRP46

1

13

High-throughput

0.479

High

919757

PXR1
Protein PXR1

1

2

Small-scale

0.479

High

923248

ESF2
Pre-rRNA-processing protein ESF2

1

1

High-throughput

0.479

High

925191

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

1

High-throughput

0.479

High

932228

ORC1
Origin recognition complex subunit 1

1

5

High-throughput

0.479

High

1046249

RRP45
Exosome complex component RRP45

1

8

High-throughput

0.479

High

1046253

SGD1
Suppressor of glycerol defect protein 1

1

6

High-throughput

0.479

High

1046260

BFR2
Protein BFR2

1

2

High-throughput

0.479

High

1046266

RRP44
Exosome complex exonuclease DIS3

1

5

High-throughput

0.479

High

1046268

RRP40
Exosome complex component RRP40

1

3

High-throughput

0.479

High

1046271

BMS1
Ribosome biogenesis protein BMS1

1

9

High-throughput

0.479

High

1046273

FCF2
rRNA-processing protein FCF2

1

1

High-throughput

0.479

High

1046274

SAS10
Something about silencing protein 10

1

1

High-throughput

0.479

High

1046276

MAK21
Ribosome biogenesis protein MAK21

1

6

High-throughput

0.479

High

1046278

RRP42
Exosome complex component RRP42

1

8

High-throughput

0.479

High

1046280

NOP56
Nucleolar protein 56

1

9

High-throughput

0.479

High

1046286

NOP14
Nucleolar complex protein 14

1

2

High-throughput

0.479

High

632918

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

1

5

High-throughput

0.470

High

814268

RV167
Reduced viability upon starvation protein 167

1

7

High-throughput

0.470

High

672941

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

673222

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.458

High

758403

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

763621

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.458

High

804953

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

818336

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

High-throughput

0.458

High

825077

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

825556

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.458

High

1046244

BUD22
Bud site selection protein 22

1

0

High-throughput

0.458

High

1046248

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

1046255

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

1046257

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.458

High

1046264

CMS1
Protein CMS1

1

0

High-throughput

0.458

High

1046265

RCL1
rRNA processing protein RCL1

1

0

High-throughput

0.458

High

1046284

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.458

High

1046287

PNO1
Pre-rRNA-processing protein PNO1

1

0

High-throughput

0.458

High

403651

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

4

High-throughput

0.457

High

531398

METK1
S-adenosylmethionine synthase 1

1

2

High-throughput

0.457

High

819727

SSB2
Ribosome-associated molecular chaperone SSB2

1

14

High-throughput

0.445

High

1027274

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

5

High-throughput

0.439

High

436511

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

6

High-throughput

0.437

High

503230

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.437

High

513571

RL1A
Large ribosomal subunit protein uL1A

1

10

High-throughput

0.437

High

515169

RL19B
Large ribosomal subunit protein eL19

1

2

High-throughput

0.437

High

580027

HSC82
ATP-dependent molecular chaperone HSC82

1

12

High-throughput

0.437

High

708106

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

748035

SMY2
Protein SMY2

1

1

High-throughput

0.437

High

748536

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

785972

LONM
Lon protease homolog, mitochondrial

1

7

High-throughput

0.437

High

812631

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

815232

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

4

High-throughput

0.437

High

826073

ULP2
Ubiquitin-like-specific protease 2

1

7

High-throughput

0.437

High

826810

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.437

High

918448

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.437

High

1025033

NUM1
Nuclear migration protein NUM1

1

10

High-throughput

0.437

High

1033552

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.437

High

1046243

VMS1
tRNA endonuclease VMS1

1

2

High-throughput

0.437

High

1046254

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

1046256

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.437

High

1046285

RS22B
Small ribosomal subunit protein uS8B

1

2

High-throughput

0.437

High

1046267

RBX1
RING-box protein HRT1

1

3

High-throughput

0.417

High

386854

TBB
Tubulin beta chain

1

12

High-throughput

0.407

High

410328

RL25
Large ribosomal subunit protein uL23

1

3

High-throughput

0.407

High

453782

PYR1
Multifunctional protein URA2

1

6

High-throughput

0.407

High

486303

TBA1
Tubulin alpha-1 chain

1

12

High-throughput

0.407

High

525070

HSP71
Heat shock protein SSA1

1

13

High-throughput

0.407

High

527610

HSP72
Heat shock protein SSA2

1

15

High-throughput

0.407

High

575518

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

4

High-throughput

0.407

High

684836

RL5
Large ribosomal subunit protein uL18

1

4

High-throughput

0.407

High

755170

GCN1
eIF-2-alpha kinase activator GCN1

1

8

High-throughput

0.407

High

817950

IMB4
Importin subunit beta-4

1

5

High-throughput

0.407

High

836885

MPG1
Mannose-1-phosphate guanyltransferase

1

3

High-throughput

0.407

High

558861

CAF20
Cap-associated protein CAF20

2

0

Small-scale

0.305

High

673276

GFD2
Good for full DBP5 activity protein 2

1

0

High-throughput

0.269

Low

805636

LSM12
Protein LSM12

1

0

High-throughput

0.269

Low

1046272

GID12
GID complex associated protein 12

1

0

High-throughput

0.269

Low

1046263

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

1046269

SGO1
Shugoshin

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025