HitPredict

Interactor 1: SIR4 (P11978)
Regulatory protein SIR4 (Silent information regulator 4)
Gene: SIR4

Interactor 2: SIR4 (P11978)
Regulatory protein SIR4 (Silent information regulator 4)
Gene: SIR4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.55 0.699

The method score is based on:

Property Details
Experiments 10757754, 1946372, 14636601, 19217406, 21822217, 16717101
Identification Methods two hybrid, x-ray crystallography, pull down, dynamic light scattering
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0003690 - double-stranded DNA binding
GO:0005677 - chromatin silencing complex
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:0030466 - silent mating-type cassette heterochromatin formation
and 7 others

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Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024