Protein: RPB11
DNA-directed RNA polymerase II subunit RPB11 (RNA polymerase II subunit B11) (B13.6) (DNA-directed RNA polymerase II 13.6 kDa polypeptide)

Gene: RPB11
Organism: Saccharomyces cerevisiae S288C
Interactions: 68
UniProt ID: P38902

Gene Ontology (top 5):
GO:0001172 - RNA-templated transcription
GO:0003677 - DNA binding
GO:0003899 - DNA-directed RNA polymerase activity
GO:0005634 - nucleus
GO:0005665 - RNA polymerase II, core complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

594362

RPB3
DNA-directed RNA polymerase II subunit RPB3

22

17

Small-scale

0.990

High

401996

RPB1
DNA-directed RNA polymerase II subunit RPB1

10

11

Small-scale

0.969

High

632341

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

6

3

Small-scale

0.933

High

470525

RPB2
DNA-directed RNA polymerase II subunit RPB2

5

9

Small-scale

0.919

High

806934

T2FB
Transcription initiation factor IIF subunit beta

8

1

Small-scale

0.746

High

632085

RPB4
DNA-directed RNA polymerase II subunit RPB4

7

2

Small-scale

0.739

High

632165

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

7

3

Small-scale

0.737

High

757321

RPB7
DNA-directed RNA polymerase II subunit RPB7

6

5

Small-scale

0.730

High

699950

RPB9
DNA-directed RNA polymerase II subunit RPB9

6

8

Small-scale

0.722

High

806958

IWR1
RNA polymerase II nuclear localization protein IWR1

5

1

Small-scale

0.712

High

694543

SPT5
Transcription elongation factor SPT5

5

1

Small-scale

0.706

High

632256

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

4

4

Small-scale

0.683

High

645052

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

4

4

Small-scale

0.683

High

806956

ASR1
Alcohol-sensitive RING finger protein 1

4

0

Small-scale

0.657

High

806933

T2FA
Transcription initiation factor IIF subunit alpha

4

0

Small-scale

0.653

High

763320

TAF14
Transcription initiation factor TFIID subunit 14

4

0

Small-scale

0.648

High

806927

RTR1
RNA polymerase II subunit B1 CTD phosphatase RTR1

3

2

Small-scale

0.640

High

806930

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

3

3

Small-scale

0.640

High

806955

CDC73
Cell division control protein 73

3

0

Small-scale

0.623

High

748286

SPT4
Transcription elongation factor SPT4

3

0

Small-scale

0.613

High

806935

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

3

0

Small-scale

0.613

High

806936

GPN1
GPN-loop GTPase 1

4

7

Small-scale

0.612

High

661164

SPT6
Transcription elongation factor SPT6

2

1

Small-scale

0.584

High

707070

TF2B
Transcription initiation factor IIB

2

5

High-throughput

0.584

High

806953

IWS1
Transcription factor SPN1

2

0

High-throughput

0.576

High

740405

MED17
Mediator of RNA polymerase II transcription subunit 17

2

0

Small-scale

0.547

High

441128

KAPA
cAMP-dependent protein kinase type 1

1

1

High-throughput

0.536

High

441363

KAPB
cAMP-dependent protein kinase type 2

1

1

High-throughput

0.536

High

806926

RSP5
E3 ubiquitin-protein ligase RSP5

1

4

High-throughput

0.536

High

454572

TFS2
Transcription elongation factor S-II

1

5

High-throughput

0.515

High

660852

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

0

High-throughput

0.513

High

806929

RAD26
DNA repair and recombination protein RAD26

1

1

Small-scale

0.501

High

806945

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.481

High

435085

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

708732

TF3B
Transcription factor IIIB 70 kDa subunit

1

5

High-throughput

0.479

High

745734

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

2

High-throughput

0.479

High

780369

ELF1
Transcription elongation factor 1

1

1

High-throughput

0.479

High

806932

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

806943

SEN1
Helicase SEN1

1

2

High-throughput

0.479

High

806944

MCE1
mRNA-capping enzyme subunit alpha

1

1

High-throughput

0.479

High

806946

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

806949

RBA50
RNA polymerase II-associated protein RBA50

1

3

High-throughput

0.479

High

806950

POB3
FACT complex subunit POB3

1

1

High-throughput

0.479

High

806952

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

408412

GAL4
Regulatory protein GAL4

1

0

Small-scale

0.460

High

739631

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.458

High

740795

MED18
Mediator of RNA polymerase II transcription subunit 18

1

0

Small-scale

0.458

High

806928

ATAD2
ATPase histone chaperone YTA7

1

0

High-throughput

0.458

High

806942

H3
Histone H3

1

0

Small-scale

0.458

High

806947

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

806959

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.458

High

743984

RAD23
UV excision repair protein RAD23

1

2

High-throughput

0.437

High

802169

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

806941

GIS2
Zinc finger protein GIS2

1

2

High-throughput

0.437

High

806954

GPN3
GPN-loop GTPase 3

1

7

Small-scale

0.437

High

806957

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

806925

CAJ1
Protein CAJ1

1

0

High-throughput

0.426

High

510478

HSP77
Import motor subunit, mitochondrial

1

3

High-throughput

0.407

High

779537

LHS1
Heat shock protein 70 homolog LHS1

1

2

High-throughput

0.407

High

806931

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.282

High

806939

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

0

High-throughput

0.282

High

806951

ERP1
Protein ERP1

1

0

High-throughput

0.282

High

806940

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.279

Low

798409

YB9F
Uncharacterized protein YBR259W

1

0

High-throughput

0.269

Low

148873

CET1
mRNA-capping enzyme subunit beta

1

0

High-throughput

0.249

Low

806938

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

806948

GPI19
Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI19

1

0

High-throughput

0.238

Low

806937

HLJ1
Protein HLJ1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025