HitPredict

Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA

Interactor 2: POLI (Q9UNA4)
DNA polymerase iota (EC 2.7.7.7) (Eta2) (RAD30 homolog B)
Gene: POLI

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.948

The method score is based on:

Property Details
Experiments 34165573, 18931444, 15342632, 26903512, 16763556, 23248005
Identification Methods affinity chromatography technology, x-ray crystallography, two hybrid, pull down, far western blotting
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IMS_C~PCNA_N
Common GO terms GO:0003684 - damaged DNA binding
GO:0005654 - nucleoplasm
GO:0019985 - translesion synthesis
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 261
Hs

1 740
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024