HitPredict

Interactor 1: RAP2A (P10114)
Ras-related protein Rap-2a (EC 3.6.5.2) (RbBP-30)
Gene: RAP2A

Interactor 2: RB40B (Q12829)
Ras-related protein Rab-40B (EC 3.6.5.2) (SOCS box-containing protein RAR) (Protein Rar)
Gene: RAB40B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	35293963
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 278
+	Hs
		959436 RAP2B_HUMAN (1-182): 1.26e-82: 243: 91.21		RB40B_HUMAN (1-278): 5.1e-103: 302: 100.00
+	Hs
		1086750 RAP2C_HUMAN (1-183): 1.82e-81: 241: 91.26		RB40B_HUMAN (1-278): 5.1e-103: 302: 100.00
+	Xl
		1220192 Q7ZX67_XENLA (16-183): 1.87e-87: 256: 98.81		Q5XHF6_XENLA (1-278): 4.34e-94: 280: 77.62
+	Hs
		1370778 RAB1B_HUMAN (4-178): 1.37e-76: 229: 34.09		RAB8B_HUMAN (8-177): 3.95e-94: 277: 43.86
+	Zm
		77342 B4FAE1_MAIZE (4-178): 1.1e-79: 237: 36.36		B4FAE1_MAIZE (7-198): 5.64e-90: 267: 36.95
+	Hs
		981254 RAB1A_HUMAN (4-183): 5.76e-80: 238: 34.25		RAB1A_HUMAN (4-197): 1.97e-87: 261: 38.05
+	Mm
		981401 RAB1A_MOUSE (4-183): 5.76e-80: 238: 34.25		RAB35_MOUSE (7-197): 4.25e-87: 259: 35.82
+	Dm
		197040 RAP1_DROME (1-165): 4.58e-81: 239: 64.24		O18332_DROME (4-197): 9.18e-86: 256: 37.07
+	Hs
		981357 RAB1A_HUMAN (4-183): 5.76e-80: 238: 34.25		RAB1B_HUMAN (7-197): 4.7e-85: 254: 37.31
+	Mm
		981416 RAB1A_MOUSE (4-183): 5.76e-80: 238: 34.25		RAB1B_MOUSE (7-197): 7.6e-85: 254: 37.81
+	Hs
		976188 RAB1A_HUMAN (4-183): 5.76e-80: 238: 34.25		RB11A_HUMAN (4-215): 7.44e-84: 252: 30.52
+	Hs
		981287 RAB1A_HUMAN (4-183): 5.76e-80: 238: 34.25		RB11B_HUMAN (4-216): 1.53e-83: 251: 31.16
+	Hs
		955910 RAB1A_HUMAN (4-183): 5.76e-80: 238: 34.25		RAB8A_HUMAN (7-205): 3.93e-83: 249: 39.00
+	Hs
		959313 RAP1B_HUMAN (1-182): 5.29e-79: 234: 60.66		RB11A_HUMAN (4-215): 7.44e-84: 252: 30.52
+	Hs
		1155389 RAB1B_HUMAN (4-178): 1.37e-76: 229: 34.09		RB11B_HUMAN (4-216): 1.53e-83: 251: 31.16
+	Hs
		902221 RAB1B_HUMAN (4-178): 1.37e-76: 229: 34.09		RAB13_HUMAN (7-197): 6.41e-83: 249: 42.19
+	Hs
		956786 RAB1B_HUMAN (4-178): 1.37e-76: 229: 34.09		RAB10_HUMAN (9-197): 4.87e-83: 249: 40.10
+	Mm
		956826 RAB1B_MOUSE (4-178): 3.3e-76: 228: 34.09		RAB10_MOUSE (9-197): 4.87e-83: 249: 40.10
+	Mm
		981396 RAB1A_MOUSE (4-183): 5.76e-80: 238: 34.25		Q3TYB1_MOUSE (9-195): 2.22e-46: 156: 43.98