HitPredict

Interactor 1: MYCL (P12524)
Protein L-Myc (Class E basic helix-loop-helix protein 38) (bHLHe38) (Protein L-Myc-1) (V-myc myelocytomatosis viral oncogene homolog)
Gene: MYCL

Interactor 2: EP400 (Q96L91)
E1A-binding protein p400 (EC 3.6.4.-) (CAG repeat protein 32) (Domino homolog) (hDomino) (Trinucleotide repeat-containing gene 12 protein) (p400 kDa SWI2/SNF2-related protein)
Gene: EP400

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	29028833, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 364 Hs			1 3159
+	Hs
		347609 MYC_HUMAN (1-362): 1e-76: 245: 29.75		EP400_HUMAN (1-3159): 0: 1399: 100.00
+	Hs
		379738 MYCN_HUMAN (1-362): 2.43e-63: 210: 31.05		EP400_HUMAN (1-3159): 0: 1399: 100.00
+	Hs
		229271 MYC_HUMAN (1-362): 1e-76: 245: 29.75		SMCA5_HUMAN (970-1548): 0: 629: 21.71
+	Hs
		346003 MYC_HUMAN (1-362): 1e-76: 245: 29.75		SMCA1_HUMAN (938-1627): 0: 623: 19.83
+	Hs
		229276 MYCN_HUMAN (1-362): 2.43e-63: 210: 31.05		SMCA5_HUMAN (970-1548): 0: 629: 21.71
+	Hs
		347406 MYC_HUMAN (1-362): 1e-76: 245: 29.75		CHD5_HUMAN (1501-2524): 1.9e-162: 558: 13.68
+	Hs
		346938 MYC_HUMAN (1-362): 1e-76: 245: 29.75		CHD9_HUMAN (1565-2538): 3.24e-144: 509: 13.41
+	Hs
		347951 MYC_HUMAN (1-362): 1e-76: 245: 29.75		CHD8_HUMAN (1521-2397): 1.55e-138: 490: 13.07
+	Hs
		347888 MYC_HUMAN (1-362): 1e-76: 245: 29.75		SMRCD_HUMAN (1895-2052): 1.85e-24: 115: 38.27
+	Hs
		347122 MYC_HUMAN (1-362): 1e-76: 245: 29.75		SRCAP_HUMAN (2495-3157): 8.1e-17: 90.5: 14.39
+	Hs
		348113 MYC_HUMAN (1-362): 1e-76: 245: 29.75		CHD7_HUMAN (2-514): 7.31e-12: 74.1: 10.60
+	Mm
		348440 MYC_MOUSE (1-362): 4.56e-78: 248: 29.98		EP400_MOUSE (2511-3159): 1.94e-10: 69.5: 10.79
+	Mm
		348422 MYC_MOUSE (1-362): 4.56e-78: 248: 29.98		SMCA4_MOUSE (2528-2890): 6.78e-09: 64.1: 11.57
+	Hs
		346267 MYC_HUMAN (1-362): 1e-76: 245: 29.75		SMCA2_HUMAN (2772-3070): 2.99e-09: 65.3: 11.65
+	Hs
		346268 MYC_HUMAN (1-362): 1e-76: 245: 29.75		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17
+	Hs
		379973 MYCN_HUMAN (1-362): 2.43e-63: 210: 31.05		CHD7_HUMAN (2-514): 7.31e-12: 74.1: 10.60
+	Hs
		379141 MYCN_HUMAN (1-362): 2.43e-63: 210: 31.05		SMCA2_HUMAN (2772-3070): 2.99e-09: 65.3: 11.65
+	Hs
		379142 MYCN_HUMAN (1-362): 2.43e-63: 210: 31.05		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17
+	Hs
		738947 SRBP1_HUMAN (35-363): 5.77e-47: 173: 14.29		SMCA2_HUMAN (2772-3070): 2.99e-09: 65.3: 11.65
+	Hs
		738948 SRBP1_HUMAN (35-363): 5.77e-47: 173: 14.29		SMCA4_HUMAN (2622-2971): 9.21e-09: 63.7: 10.17