Interactor 1: BMP2 (P12643)
Bone morphogenetic protein 2 (BMP-2) (Bone morphogenetic protein 2A) (BMP-2A)
Gene: BMP2
Interactor 2: BMR1A (P36894)
Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)
Gene: BMPR1A
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.987 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11263668, 18070108, 10692589, 10880444, 10712517, 16672363, 10881198, 25938661, 17483092, 18937504, 15064755, 19804412, 20860622, 21054789 |
| Identification Methods | x-ray crystallography, pull down, molecular sieving, surface plasmon resonance, light scattering, nuclear magnetic resonance, isothermal titration calorimetry, enzyme linked immunosorbent assay, competition binding, cross-linking study and 1 others
more... |
| Interaction Type | association, direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Activin_recp~TGF_beta |
| Common GO terms | GO:0001649 - osteoblast differentiation GO:0001701 - in utero embryonic development GO:0002062 - chondrocyte differentiation GO:0003203 - endocardial cushion morphogenesis GO:0003272 - endocardial cushion formation and 10 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
