HitPredict

Interactor 1: ARAF (P10398)
Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks)
Gene: ARAF

Interactor 2: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	30196744, 31015422
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 606 Hs			1 607
+	Hs
		400986 RAF1_HUMAN (12-606): 0: 527: 60.27		A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00
+	Hs
		1227009 KSR1_HUMAN (50-606): 2.17e-122: 385: 24.24		A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00
+	Hs
		463126 YES_HUMAN (289-568): 3.28e-104: 327: 31.34		A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00
+	Hs
		401279 RAF1_HUMAN (12-606): 0: 527: 60.27		SNR40_HUMAN (175-514): 4.64e-64: 216: 16.81
+	Hs
		400592 RAF1_HUMAN (12-606): 0: 527: 60.27		WDR5_HUMAN (177-474): 3.11e-58: 200: 17.43
+	Hs
		400614 RAF1_HUMAN (12-606): 0: 527: 60.27		GBB2_HUMAN (164-516): 1.54e-55: 193: 16.30
+	Hs
		400994 RAF1_HUMAN (12-606): 0: 527: 60.27		Q6FHM2_HUMAN (165-516): 5.48e-44: 162: 16.62
+	Hs
		400613 RAF1_HUMAN (12-606): 0: 527: 60.27		GBB1_HUMAN (165-516): 2.35e-43: 160: 17.18
+	Mm
		411154 ARAF_MOUSE (1-606): 0: 554: 94.88		A16L1_MOUSE (436-605): 1.39e-26: 116: 15.25
+	Hs
		578540 BRAF_HUMAN (3-604): 0: 537: 54.78		TBL1R_HUMAN (479-607): 3.68e-24: 108: 18.71
+	Hs
		440596 FYN_HUMAN (303-568): 1.52e-37: 148: 33.46		A16L1_HUMAN (1-607): 2.11e-166: 489: 100.00
+	Hs
		440523 FYN_HUMAN (303-568): 1.52e-37: 148: 33.46		STRN3_HUMAN (14-603): 3.47e-97: 316: 12.99
+	Hs
		440671 FYN_HUMAN (303-568): 1.52e-37: 148: 33.46		SNR40_HUMAN (175-514): 4.64e-64: 216: 16.81
+	Hs
		440480 FYN_HUMAN (303-568): 1.52e-37: 148: 33.46		GBB1_HUMAN (165-516): 2.35e-43: 160: 17.18
+	Hs
		841003 FRK_HUMAN (303-568): 1.35e-36: 145: 33.70		GBB1_HUMAN (165-516): 2.35e-43: 160: 17.18
+	Hs
		1250423 KSR2_HUMAN (303-584): 2.03e-45: 174: 36.30		TBL1R_HUMAN (479-607): 3.68e-24: 108: 18.71