Interactor 1: CADH1 (P12830)
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]
Gene: CDH1

Interactor 2: DSG2 (Q14126)
Desmoglein-2 (Cadherin family member 5) (HDGC)
Gene: DSG2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 25468996
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cadherin~Cadherin
Common GO terms GO:0005509 - calcium ion binding
GO:0005886 - plasma membrane
GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules
GO:0016328 - lateral plasma membrane
GO:0030054 - cell junction
and 3 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 882
Hs

1 1118
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Last updated: 15 Jul 2024