Interactor 1: CAN3 (P20807)
Calpain-3 (EC 3.4.22.54) (Calcium-activated neutral proteinase 3) (CANP 3) (Calpain L3) (Calpain p94) (Muscle-specific calcium-activated neutral protease 3) (New calpain 1) (nCL-1)
Gene: CAPN3
Interactor 2: CAN3 (P20807)
Calpain-3 (EC 3.4.22.54) (Calcium-activated neutral proteinase 3) (CANP 3) (Calpain L3) (Calpain p94) (Muscle-specific calcium-activated neutral protease 3) (New calpain 1) (nCL-1)
Gene: CAPN3
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.72 | 1.00 | 0.849 |
The method score is based on:
Property | Details |
---|---|
Experiments | 32296183, unassigned1304, 24846670 |
Identification Methods | two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, x-ray crystallography |
Interaction Type | direct interaction, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Calpain_III~EF-hand_8, Calpain_III~Peptidase_C2, EF-hand_6~EF-hand_6, EF-hand_6~EF-hand_8, EF-hand_8~EF-hand_8, Peptidase_C2~Peptidase_C2 |
Common GO terms | GO:0003824 - catalytic activity GO:0004198 - calcium-dependent cysteine-type endopeptidase activity GO:0005509 - calcium ion binding GO:0005634 - nucleus GO:0005730 - nucleolus and 43 others more... |
Homologous interactions | 14 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024