Interactor 1: BCL2 (P10415)
Apoptosis regulator Bcl-2
Gene: BCL2
Interactor 2: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.70 | 1.00 | 0.839 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18719108, 8668206 |
| Identification Methods | unspecified method, pull down, two hybrid, biochemical, peptide array, affinity chromatography technology, fluorescence technology, coimmunoprecipitation, proximity ligation assay, surface plasmon resonance |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ank_2~Bcl-2 |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
