HitPredict

Interactor 1: CCL4 (P13236)
C-C motif chemokine 4 (G-26 T-lymphocyte-secreted protein) (HC21) (Lymphocyte activation gene 1 protein) (LAG-1) (MIP-1-beta(1-69)) (Macrophage inflammatory protein 1-beta) (MIP-1-beta) (PAT 744) (Protein H400) (SIS-gamma) (Small-inducible cytokine A4) (T-cell activation protein 2) (ACT-2) [Cleaved into: MIP-1-beta(3-69)]
Gene: CCL4

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22030901
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006954 - inflammatory response GO:0071347 - cellular response to interleukin-1 GO:0071356 - cellular response to tumor necrosis factor
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 92 Hs			1 551
+	Hs
		978774 CCL14_HUMAN (1-92): 2.01e-35: 117: 43.01		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		528216 CCL2_HUMAN (1-90): 1.12e-28: 100: 36.26		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		528260 CCL5_HUMAN (1-92): 1.14e-27: 97.7: 45.65		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		943970 X3CL1_HUMAN (8-91): 7.16e-23: 91.9: 27.59		TF65_HUMAN (1-551): 0: 601: 100.00
+	Mm
		486360 CCL2_MOUSE (1-92): 6.78e-34: 115: 39.79		TF65_MOUSE (1-551): 0: 577: 87.88
+	Mm
		677067 CCL5_MOUSE (1-92): 7.06e-33: 110: 48.91		TF65_MOUSE (1-551): 0: 577: 87.88
+	Hs
		134732 CCL22_HUMAN (21-91): 1.92e-21: 81.9: 34.72		TF65_HUMAN (1-551): 0: 601: 100.00
+	Mm
		292678 CCL20_MOUSE (2-91): 4.12e-20: 78.8: 33.70		TF65_MOUSE (1-551): 0: 577: 87.88
+	Mm
		486356 CCL2_MOUSE (1-92): 6.78e-34: 115: 39.79		NFKB1_MOUSE (7-451): 3.1e-157: 475: 30.19
+	Mm
		638438 CCL5_MOUSE (1-92): 7.06e-33: 110: 48.91		NFKB1_MOUSE (7-451): 3.1e-157: 475: 30.19
+	Hs
		587597 CCL14_HUMAN (1-92): 2.01e-35: 117: 43.01		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		528261 CCL5_HUMAN (1-92): 1.14e-27: 97.7: 45.65		REL_HUMAN (12-523): 3.56e-165: 484: 41.64
+	Hs
		528199 CCL2_HUMAN (1-90): 1.12e-28: 100: 36.26		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		587476 CCL11_HUMAN (1-91): 5.56e-27: 96.2: 40.22		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		528259 CCL5_HUMAN (1-92): 1.14e-27: 97.7: 45.65		RELB_HUMAN (3-461): 2.62e-154: 455: 40.00
+	Hs
		134722 CCL22_HUMAN (21-91): 1.92e-21: 81.9: 34.72		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		964508 CCL17_HUMAN (7-90): 3.88e-24: 88.8: 29.76		RELB_HUMAN (3-461): 2.62e-154: 455: 40.00
+	Hs
		587691 CCL19_HUMAN (17-91): 1.05e-19: 77.7: 33.77		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		134731 CCL22_HUMAN (21-91): 1.92e-21: 81.9: 34.72		RELB_HUMAN (3-461): 2.62e-154: 455: 40.00
+	Mm
		486364 CCL2_MOUSE (1-92): 6.78e-34: 115: 39.79		NFAT5_MOUSE (6-471): 3.35e-100: 333: 17.26