Protein: TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit (EC 2.4.1.15) (General glucose sensor subunit 1) (Glycogen metabolism control protein GLC6) (Trehalose synthase complex catalytic subunit TPS1) (Trehalose-6-phosphate synthase) (UDP-glucose-glucosephosphate glucosyltransferase)

Gene: TPS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 91
UniProt ID: Q00764

Gene Ontology (top 5):
GO:0003825 - alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity
GO:0004805 - trehalose-phosphatase activity
GO:0005737 - cytoplasm
GO:0005946 - alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)
GO:0005975 - carbohydrate metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

727683

TPS2
Trehalose-phosphatase

7

14

Small-scale

0.966

High

799670

TPS3
Trehalose synthase complex regulatory subunit TPS3

6

16

Small-scale

0.951

High

799692

TSL1
Trehalose synthase complex regulatory subunit TSL1

6

16

Small-scale

0.951

High

1026962

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

2

14

Small-scale

0.778

High

819517

SSB2
Ribosome-associated molecular chaperone SSB2

3

6

High-throughput

0.634

High

527438

HSP72
Heat shock protein SSA2

3

8

High-throughput

0.624

High

545919

SSB1
Ribosome-associated molecular chaperone SSB1

3

6

High-throughput

0.624

High

742186

HSP7F
Heat shock protein homolog SSE1

3

10

High-throughput

0.624

High

518366

IF4A
ATP-dependent RNA helicase eIF4A

2

0

High-throughput

0.595

High

713024

MCM2
DNA replication licensing factor MCM2

2

0

High-throughput

0.595

High

733675

GLNA
Glutamine synthetase

2

0

High-throughput

0.595

High

756611

MKS1
Negative regulator of RAS-cAMP pathway

2

0

High-throughput

0.595

High

798493

KDSR
3-ketodihydrosphingosine reductase TSC10

2

0

High-throughput

0.595

High

1026963

REG1
Resistance to glucose repression protein 1

2

0

High-throughput

0.595

High

393180

HSP82
ATP-dependent molecular chaperone HSP82

2

5

High-throughput

0.584

High

579904

HSC82
ATP-dependent molecular chaperone HSC82

2

5

High-throughput

0.584

High

752613

HSP78
Heat shock protein 78, mitochondrial

2

3

High-throughput

0.571

High

824609

YIR7
Y' element ATP-dependent helicase YIL177C

2

0

High-throughput

0.563

High

1026968

GTO3
Glutathione S-transferase omega-like 3

2

0

High-throughput

0.563

High

524860

HSP71
Heat shock protein SSA1

2

8

High-throughput

0.552

High

440965

CDC7
Cell division control protein 7

1

6

High-throughput

0.536

High

518107

SSBP1
Single-stranded nucleic acid-binding protein

1

1

High-throughput

0.536

High

735274

KNS1
Dual specificity protein kinase KNS1

1

10

High-throughput

0.536

High

800622

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

2

High-throughput

0.536

High

1026966

VHS1
Serine/threonine-protein kinase VHS1

1

11

High-throughput

0.536

High

850150

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.533

High

818040

LSM4
LSM complex subunit LSM4

1

0

High-throughput

0.513

High

1026797

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.513

High

1026974

RBX1
RING-box protein HRT1

1

0

High-throughput

0.513

High

1026971

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.493

High

625040

PRP6
Pre-mRNA-splicing factor 6

1

2

High-throughput

0.489

High

678787

PDP2
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

1

1

High-throughput

0.489

High

1026969

RRP5
rRNA biogenesis protein RRP5

1

1

High-throughput

0.489

High

849768

RIM15
Serine/threonine-protein kinase RIM15

1

0

Small-scale

0.486

High

645767

HSP74
Heat shock protein SSA4

1

8

High-throughput

0.479

High

671020

SIS1
Protein SIS1

1

6

High-throughput

0.479

High

694159

CDC15
Cell division control protein 15

1

10

High-throughput

0.479

High

727250

HS104
Heat shock protein 104

1

3

High-throughput

0.479

High

747998

SMY2
Protein SMY2

1

3

High-throughput

0.479

High

803653

RPN1
26S proteasome regulatory subunit RPN1

1

2

High-throughput

0.479

High

918652

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

1026978

SIZ2
E3 SUMO-protein ligase SIZ2

1

1

High-throughput

0.479

High

762863

TOR1
Serine/threonine-protein kinase TOR1

1

0

High-throughput

0.460

High

806340

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.460

High

1026977

RIO1
Serine/threonine-protein kinase RIO1

1

0

Small-scale

0.460

High

435288

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

802324

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

815208

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

874468

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

922643

HST2
NAD-dependent protein deacetylase HST2

1

0

High-throughput

0.458

High

1026965

VPS60
Vacuolar protein-sorting-associated protein 60

1

0

Small-scale

0.458

High

1026975

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.458

High

676263

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.445

High

679971

CDC48
Cell division control protein 48

1

3

High-throughput

0.437

High

707914

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

747522

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

795153

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

806797

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.437

High

812567

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

897490

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.437

High

922106

COPA
Coatomer subunit alpha

1

3

High-throughput

0.437

High

1026970

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

1

High-throughput

0.437

High

452681

ADH3
Alcohol dehydrogenase 3, mitochondrial

1

0

High-throughput

0.426

High

826472

DJP1
DnaJ-like protein 1

1

3

High-throughput

0.407

High

858048

RSSA2
Small ribosomal subunit protein uS2B

1

1

High-throughput

0.407

High

866242

IML1
Vacuolar membrane-associated protein IML1

2

0

High-throughput

0.324

High

737134

ALLA
Ureidoglycolate lyase

2

0

High-throughput

0.307

High

1026972

CTR3
Copper transport protein CTR3

2

0

High-throughput

0.307

High

645967

DBF2
Cell cycle protein kinase DBF2

1

0

High-throughput

0.279

Low

748191

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.279

Low

763002

SPT7
SAGA complex subunit SPT7

1

0

High-throughput

0.279

Low

779630

VPS21
Vacuolar protein sorting-associated protein 21

1

0

High-throughput

0.279

Low

1026967

KU80
ATP-dependent DNA helicase II subunit 2

1

0

High-throughput

0.279

Low

607780

HXKG
Glucokinase-1

1

0

High-throughput

0.269

Low

1026973

NOC3
Nucleolar complex-associated protein 3

1

0

High-throughput

0.269

Low

836319

BNI1
Protein BNI1

1

0

High-throughput

0.261

Low

410282

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

433793

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

442059

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

455207

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

504363

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

513158

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

808536

TEM1
Protein TEM1

1

0

High-throughput

0.249

Low

1026964

ULP1
Ubiquitin-like-specific protease 1

1

0

High-throughput

0.249

Low

1026976

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

1026979

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low

634266

NUP1
Nucleoporin NUP1

1

0

High-throughput

0.238

Low

843228

ZIM17
Mitochondrial protein import protein ZIM17

1

0

High-throughput

0.238

Low

642069

DPOE
DNA polymerase epsilon catalytic subunit A

1

0

High-throughput

0.232

Low

798066

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025