Protein: TPS2
Trehalose-phosphatase (EC 3.1.3.12) (Trehalose synthase complex catalytic subunit TPS2) (Trehalose-6-phosphate phosphatase) (TPP)

Gene: TPS2
Organism: Saccharomyces cerevisiae S288C
Interactions: 40
UniProt ID: P31688

Gene Ontology (top 5):
GO:0004805 - trehalose-phosphatase activity
GO:0005739 - mitochondrion
GO:0005946 - alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)
GO:0005991 - trehalose metabolic process
GO:0005992 - trehalose biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

727683

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

7

14

Small-scale

0.966

High

727670

TPS3
Trehalose synthase complex regulatory subunit TPS3

6

14

Small-scale

0.948

High

727671

TSL1
Trehalose synthase complex regulatory subunit TSL1

4

14

Small-scale

0.900

High

727664

TPS2
Trehalose-phosphatase

2

14

Small-scale

0.762

High

727680

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.584

High

544108

SSB1
Ribosome-associated molecular chaperone SSB1

2

6

High-throughput

0.521

High

594905

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

High-throughput

0.513

High

579008

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

679464

CDC48
Cell division control protein 48

1

3

High-throughput

0.479

High

727667

LAS1
Protein LAS1

1

1

Small-scale

0.479

High

727675

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

3

High-throughput

0.479

High

670441

SIS1
Protein SIS1

1

6

High-throughput

0.470

High

727684

SYF1
Pre-mRNA-splicing factor SYF1

1

2

High-throughput

0.470

High

656714

KC12
Casein kinase I homolog 2

1

7

High-throughput

0.457

High

727672

KSP1
Serine/threonine-protein kinase KSP1

1

12

High-throughput

0.457

High

526137

HSP72
Heat shock protein SSA2

1

8

High-throughput

0.445

High

727687

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

392384

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.437

High

649579

KCC2
Calcium/calmodulin-dependent protein kinase II

1

1

High-throughput

0.437

High

706442

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

713213

SEC65
Signal recognition particle subunit SEC65

1

2

High-throughput

0.437

High

727666

SMY2
Protein SMY2

1

3

High-throughput

0.437

High

727668

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

727673

MUP3
Low-affinity methionine permease

1

2

High-throughput

0.437

High

727674

RPN1
26S proteasome regulatory subunit RPN1

1

2

High-throughput

0.437

High

727677

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.437

High

727678

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

727682

COPA
Coatomer subunit alpha

1

3

High-throughput

0.437

High

727686

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

523309

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.407

High

727665

HSP7F
Heat shock protein homolog SSE1

1

10

High-throughput

0.407

High

727685

HSP31
Glutathione-independent glyoxalase HSP31

1

1

High-throughput

0.407

High

727676

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.279

Low

727681

SC6B2
Protein transport protein SBH2

1

0

High-throughput

0.265

Low

511094

YA066
Putative GPI-anchored protein YAR066W

1

0

High-throughput

0.251

Low

727669

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

727679

MOB1
DBF2 kinase activator protein MOB1

1

0

High-throughput

0.249

Low

727688

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

727689

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025