Protein: TPS3
Trehalose synthase complex regulatory subunit TPS3 (Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 115 kDa subunit)

Gene: TPS3
Organism: Saccharomyces cerevisiae S288C
Interactions: 43
UniProt ID: P38426

Gene Ontology (top 5):
GO:0003824 - catalytic activity
GO:0005737 - cytoplasm
GO:0005946 - alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)
GO:0005992 - trehalose biosynthetic process
GO:0030234 - enzyme regulator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

799670

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

6

16

Small-scale

0.951

High

727670

TPS2
Trehalose-phosphatase

6

14

Small-scale

0.948

High

799658

TPS3
Trehalose synthase complex regulatory subunit TPS3

4

16

Small-scale

0.880

High

799659

TSL1
Trehalose synthase complex regulatory subunit TSL1

3

16

High-throughput

0.836

High

526566

HSP72
Heat shock protein SSA2

2

8

High-throughput

0.552

High

799665

SSB2
Ribosome-associated molecular chaperone SSB2

2

6

High-throughput

0.552

High

523793

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.536

High

799666

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.533

High

799674

YL345
Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase YLR345W [Includes: 6-phosphofructo-2-kinase

1

0

High-throughput

0.518

High

509523

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

4

High-throughput

0.501

High

579308

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

723603

MLS1
Malate synthase 1

1

1

High-throughput

0.479

High

747825

SMY2
Protein SMY2

1

3

High-throughput

0.479

High

795314

ATG8
Autophagy-related protein 8

1

1

High-throughput

0.479

High

795708

PLPHP
Pyridoxal phosphate homeostasis protein

1

1

High-throughput

0.479

High

670642

SIS1
Protein SIS1

1

6

High-throughput

0.470

High

623846

MYO2
Myosin-2

1

0

Small-scale

0.460

High

460967

LTE1
Guanine nucleotide exchange factor LTE1

1

0

High-throughput

0.458

High

737840

HOG1
Mitogen-activated protein kinase HOG1

1

0

High-throughput

0.458

High

799667

TIM54
Mitochondrial import inner membrane translocase subunit TIM54

1

0

High-throughput

0.458

High

799671

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

453569

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.445

High

544701

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.445

High

675964

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.445

High

752201

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.445

High

679624

CDC48
Cell division control protein 48

1

3

High-throughput

0.437

High

706963

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

713222

SEC65
Signal recognition particle subunit SEC65

1

2

High-throughput

0.437

High

793591

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

2

High-throughput

0.437

High

799660

MUP3
Low-affinity methionine permease

1

2

High-throughput

0.437

High

799661

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

3

High-throughput

0.437

High

799664

NSA2
Ribosome biogenesis protein NSA2

1

1

High-throughput

0.437

High

799669

COPA
Coatomer subunit alpha

1

3

High-throughput

0.437

High

799675

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

799663

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.426

High

793911

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

0

High-throughput

0.279

Low

360977

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

High-throughput

0.249

Low

799662

GDI1
Rab GDP-dissociation inhibitor

1

0

High-throughput

0.249

Low

799668

HFM1
ATP-dependent DNA helicase MER3

1

0

Small-scale

0.249

Low

799672

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

799673

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.249

Low

799676

JID1
J domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025