Interactor 1: DPOLA (P13382)
DNA polymerase alpha catalytic subunit A (EC 2.7.7.7) (DNA polymerase I subunit A) (DNA polymerase alpha:primase complex p180 subunit) (DNA polymerase-primase complex p180 subunit) (Pol alpha-primase complex p180 subunit)
Gene: POL1

Interactor 2: CTF4 (Q01454)
DNA polymerase alpha-binding protein (Chromosome replication protein CHL15) (Chromosome transmission fidelity protein 4) (Protein POB1)
Gene: CTF4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.765

The method score is based on:

Property Details
Experiments 24805245, 9199353, 1448101, 25697176, 27397686, 27397685, 31589141, 19661920, 15485923, 30104407, 18719252, 22433841, 22593576, 23334284
Identification Methods mass spectrometry studies of complexes, x-ray crystallography, cosedimentation through density gradient, affinity chromatography technology, classical fluorescence spectroscopy, pull down, coimmunoprecipitation, transmission electron microscopy, anti tag coimmunoprecipitation, unspecified method and 2 others

more...

Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003682 - chromatin binding
GO:0006270 - DNA replication initiation
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 1468
Sc

1 927
+ Hs
+ Xl
+ Xl
+ Sp
+ Dm
+ Hs
+ Sc

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Last updated: 15 Jul 2024