HitPredict

Interactor 1: RB (P13405)
Retinoblastoma-associated protein (p110-RB1) (pRb) (Rb) (pp105)
Gene: Rb1

Interactor 2: CDK4 (P30285)
Cyclin-dependent kinase 4 (EC 2.7.11.22) (CRK3) (Cell division protein kinase 4) (PSK-J3)
Gene: CDK4

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.655

The method score is based on:

Property Details
Experiments 15158336, 8547220, 11254678
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005667 - transcription regulator complex
and 2 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 921
Mm

1 303
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ At
+ At
+ At
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024