HitPredict

Interactor 1: MYH6 (P13533)
Myosin-6 (Myosin heavy chain 6) (Myosin heavy chain, cardiac muscle alpha isoform) (MyHC-alpha)
Gene: MYH6

Interactor 2: CDK3 (Q00526)
Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)
Gene: CDK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1939 Hs			1 305
+	Hs
		625177 MYH10_HUMAN (26-1928): 0: 1015: 40.10		CDK2_HUMAN (1-292): 1.87e-148: 420: 76.71
+	Hs
		725114 MYH10_HUMAN (26-1928): 0: 1015: 40.10		CDK7_HUMAN (3-296): 2.86e-124: 360: 45.64
+	Hs
		960129 MYH13_HUMAN (1035-1939): 7.94e-63: 240: 17.02		CDK3_HUMAN (1-305): 1.8e-151: 427: 100.00
+	Hs
		522604 MYH7_HUMAN (725-1816): 1.63e-62: 239: 17.14		CDK3_HUMAN (1-305): 1.8e-151: 427: 100.00
+	Hs
		960130 MYH15_HUMAN (927-1939): 7.98e-60: 230: 16.70		CDK3_HUMAN (1-305): 1.8e-151: 427: 100.00
+	Hs
		528405 MYH8_HUMAN (1014-1939): 3.73e-59: 228: 15.86		CDK3_HUMAN (1-305): 1.8e-151: 427: 100.00
+	Hs
		528401 MYH8_HUMAN (1014-1939): 3.73e-59: 228: 15.86		CDK2_HUMAN (1-292): 1.87e-148: 420: 76.71
+	Hs
		960128 MYH2_HUMAN (1067-1939): 8.69e-56: 217: 15.24		CDK3_HUMAN (1-305): 1.8e-151: 427: 100.00
+	Hs
		625176 MYH9_HUMAN (1074-1939): 5.95e-55: 214: 16.42		CDK2_HUMAN (1-292): 1.87e-148: 420: 76.71
+	Hs
		522542 MYH1_HUMAN (1102-1939): 1.21e-51: 204: 16.43		CDK3_HUMAN (1-305): 1.8e-151: 427: 100.00
+	Hs
		724717 MYH9_HUMAN (1074-1939): 5.95e-55: 214: 16.42		CDK7_HUMAN (3-296): 2.86e-124: 360: 45.64
+	Hs
		502908 MYH3_HUMAN (730-1405): 7.93e-31: 135: 14.90		CDK3_HUMAN (1-305): 1.8e-151: 427: 100.00