HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: ACTH (P63267)
Actin, gamma-enteric smooth muscle (EC 3.6.4.-) (Alpha-actin-3) (Gamma-2-actin) (Smooth muscle gamma-actin) [Cleaved into: Actin, gamma-enteric smooth muscle, intermediate form]
Gene: ACTG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	31324722
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 376
+	Hs
		529215 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ACTBL_HUMAN (1-376): 0: 713: 87.77
+	Hs
		528863 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ACTB_HUMAN (1-376): 0: 601: 93.35
+	Hs
		528948 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ACTG_HUMAN (3-376): 0: 601: 94.39
+	Hs
		528913 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ACTA_HUMAN (1-376): 0: 595: 99.20