Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR
Interactor 2: GOPC (Q9HD26)
Golgi-associated PDZ and coiled-coil motif-containing protein (CFTR-associated ligand) (Fused in glioblastoma) (PDZ protein interacting specifically with TC10) (PIST)
Gene: GOPC
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 0.60 | 0.749 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12471024, 11707463, 31324722, 17158866, 18754678, 16331976, 28360110 |
| Identification Methods | pull down, two hybrid, affinity chromatography technology, peptide array, fluorescence polarization spectroscopy, nuclear magnetic resonance, anti tag coimmunoprecipitation, cross-linking study |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005737 - cytoplasm GO:0005765 - lysosomal membrane GO:0005886 - plasma membrane GO:0016020 - membrane GO:0030660 - Golgi-associated vesicle membrane and 1 others more... |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
