HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: SAFB1 (Q15424)
Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein)
Gene: SAFB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003690 - double-stranded DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0043565 - sequence-specific DNA binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 915
+	Hs
		530442 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MDN1_HUMAN (63-707): 1.61e-64: 239: 11.64
+	Hs
		530203 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MSI2H_HUMAN (297-588): 2.11e-53: 191: 12.96
+	Hs
		529736 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PABP4_HUMAN (258-499): 1.68e-40: 161: 15.69
+	Hs
		528957 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PABP1_HUMAN (258-499): 8e-38: 153: 14.12
+	Hs
		214273 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		MSI1H_HUMAN (300-495): 1e-37: 147: 18.18
+	Mm
		530834 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		Q62029_MOUSE (396-859): 1.09e-43: 170: 8.85
+	Rn
		620098 TAU_RAT (1-758): 3.21e-76: 263: 72.11		PABP1_RAT (258-499): 9.5e-38: 152: 14.51
+	Rn
		98792 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		PABP1_RAT (258-499): 9.5e-38: 152: 14.51
+	Hs
		698379 MAP4_HUMAN (22-721): 3.01e-10: 66.2: 9.24		SLTM_HUMAN (29-828): 1.64e-50: 195: 30.24
+	Hs
		550367 KMT2C_HUMAN (228-752): 7.28e-09: 62: 7.94		PABP1_HUMAN (258-499): 8e-38: 153: 14.12
+	Hs
		65312 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		RFOX3_HUMAN (307-501): 3.09e-30: 124: 20.00