Interactor 1: KRAF1 (P11346)
Raf homolog serine/threonine-protein kinase Raf (D-Raf) (dRAF-1) (EC 2.7.11.1) (Protein pole-hole)
Gene: Raf
Interactor 2: GRAP (Q08012)
Growth factor receptor-bound protein 2 (Downstream of receptor kinase) (Protein enhancer of sevenless 2B)
Gene: drk
Species: Drosophila melanogaster
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22028469 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C1_1~SH2, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0007173 - epidermal growth factor receptor signaling pathway GO:0007265 - Ras protein signal transduction GO:0007427 - epithelial cell migration, open tracheal system and 7 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025