Interactor 1: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.980

The method score is based on:

Property Details
Experiments 15456896, 14670955, 19789182, 29434030, 31420536, 31980649, 32917811, 21335603, 15020686, 12606547, 11078745, 17254967, 17170700, 14993658, 25117710
Identification Methods enzymatic study, affinity chromatography technology, protein kinase assay
Interaction Type direct interaction, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1, SH2~SH2, SH2~SH3_1, SH3_1~SH3_1
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0002102 - podosome
GO:0002223 - stimulatory C-type lectin receptor signaling pathway
GO:0002862 - negative regulation of inflammatory response to antigenic stimulus
GO:0004672 - protein kinase activity
and 117 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 536
Hs

1 536
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Service provided by Combinatics, Japan

Last updated: 11Aug2025