HitPredict

Interactor 1: RARA (P11416)
Retinoic acid receptor alpha (RAR-alpha) (Nuclear receptor subfamily 1 group B member 1)
Gene: RARA

Interactor 2: DDX1 (Q91VR5)
ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1)
Gene: DDX1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	18495661
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 462 Mm			1 740
+	Hs
		396613 ESR1_HUMAN (7-461): 4.99e-118: 359: 22.40		DDX1_HUMAN (1-740): 0: 574: 97.57
+	Mm
		542861 RARA_MOUSE (1-462): 2.19e-152: 443: 100.00		DDX3X_MOUSE (1-380): 2.18e-49: 186: 14.71
+	Mm
		542869 RARA_MOUSE (1-462): 2.19e-152: 443: 100.00		Q8BTS0_MOUSE (1-380): 2.02e-43: 168: 12.25
+	Hs
		141357 HNF4A_HUMAN (78-462): 1.29e-123: 369: 24.45		DDX3X_HUMAN (1-380): 5.04e-49: 185: 14.96
+	Hs
		141269 ESR1_HUMAN (7-461): 4.99e-118: 359: 22.40		DDX3X_HUMAN (1-380): 5.04e-49: 185: 14.96
+	Hs
		193080 ESR1_HUMAN (7-461): 4.99e-118: 359: 22.40		DDX3Y_HUMAN (1-380): 3.96e-48: 182: 14.71
+	Hs
		193098 ERR3_HUMAN (13-417): 3.62e-119: 357: 30.30		DDX3Y_HUMAN (1-380): 3.96e-48: 182: 14.71
+	Hs
		396649 ESR1_HUMAN (7-461): 4.99e-118: 359: 22.40		DDX17_HUMAN (1-380): 9.16e-45: 173: 13.01
+	Hs
		395450 ESR1_HUMAN (7-461): 4.99e-118: 359: 22.40		DDX5_HUMAN (1-380): 2.01e-43: 168: 12.25
+	Hs
		141592 ESR2_HUMAN (3-448): 3.29e-107: 329: 24.95		DDX3X_HUMAN (1-380): 5.04e-49: 185: 14.96
+	Hs
		141324 NR4A1_HUMAN (16-420): 1.81e-103: 322: 30.02		DDX3X_HUMAN (1-380): 5.04e-49: 185: 14.96
+	Hs
		608452 NR4A1_HUMAN (16-420): 1.81e-103: 322: 30.02		DDX5_HUMAN (1-380): 2.01e-43: 168: 12.25
+	Hs
		395619 ESR1_HUMAN (7-461): 4.99e-118: 359: 22.40		IF4A3_HUMAN (3-72): 3.37e-11: 67.8: 30.00
+	Hs
		807515 ESR2_HUMAN (3-448): 3.29e-107: 329: 24.95		IF4A3_HUMAN (3-72): 3.37e-11: 67.8: 30.00
+	Hs
		789541 PPARG_HUMAN (66-416): 7.54e-48: 173: 31.03		DDX17_HUMAN (1-380): 9.16e-45: 173: 13.01