HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: CMR1 (Q12510)
DNA damage-binding protein CMR1 (Changed mutation rate protein 1)
Gene: CMR1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	25817432
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 522
+	Sc
		367137 HSP82_YEAST (1-705): 0: 968: 95.63		CMR1_YEAST (1-522): 7.95e-112: 343: 100.00
+	Hs
		432270 HS90A_HUMAN (4-705): 0: 1013: 60.67		WDR76_HUMAN (4-515): 2.47e-92: 296: 22.98
+	Hs
		538405 ENPL_HUMAN (3-680): 0: 893: 47.10		WDR76_HUMAN (4-515): 2.47e-92: 296: 22.98
+	Hs
		437971 HS90B_HUMAN (5-705): 0: 1022: 61.15		LIS1_HUMAN (329-521): 1.15e-38: 147: 13.33
+	Hs
		431630 HS90A_HUMAN (4-705): 0: 1013: 60.67		LIS1_HUMAN (329-521): 1.15e-38: 147: 13.33
+	Hs
		438048 HS90B_HUMAN (5-705): 0: 1022: 61.15		WDR5_HUMAN (365-520): 1.09e-35: 137: 13.29
+	Ca
		483034 HSP90_CANAL (4-705): 0: 953: 82.36		TUP1_CANAL (287-520): 4.06e-47: 173: 12.89
+	Hs
		538141 ENPL_HUMAN (3-680): 0: 893: 47.10		LIS1_HUMAN (329-521): 1.15e-38: 147: 13.33
+	Hs
		538184 ENPL_HUMAN (3-680): 0: 893: 47.10		WDR5_HUMAN (365-520): 1.09e-35: 137: 13.29