HitPredict

Interactor 1: MYOD1 (P15172)
Myoblast determination protein 1 (Class C basic helix-loop-helix protein 1) (bHLHc1) (Myogenic factor 3) (Myf-3)
Gene: MYOD1

Interactor 2: CSRP3 (P50461)
Cysteine and glycine-rich protein 3 (Cardiac LIM protein) (Cysteine-rich protein 3) (CRP3) (LIM domain protein, cardiac) (Muscle LIM protein)
Gene: CSRP3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	1.00	0.821

Property	Details
Experiments	9234731, 24860983
Identification Methods	affinity chromatography technology, pull down, two hybrid, far western blotting
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	HLH~LIM
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0007519 - skeletal muscle tissue development GO:0045663 - positive regulation of myoblast differentiation GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 320 Hs			1 194
+	Hs
		616612 MYF6_HUMAN (23-269): 1.47e-48: 164: 36.15		CSRP3_HUMAN (1-194): 2.52e-43: 144: 100.00
+	Rn
		582055 MYF6_RAT (23-269): 1.99e-46: 159: 34.94		CSRP3_RAT (1-194): 1.33e-41: 140: 95.88
+	Hs
		546074 MYOG_HUMAN (23-279): 1.96e-43: 150: 35.02		CSRP3_HUMAN (1-194): 2.52e-43: 144: 100.00
+	Hs
		1044669 ATOH1_HUMAN (91-303): 3.82e-41: 148: 22.43		FHL3_HUMAN (35-179): 8.46e-14: 69.8: 23.57