Interactor 1: KCNJ6 (P48542)
G protein-activated inward rectifier potassium channel 2 (GIRK-2) (Inward rectifier K(+) channel Kir3.2) (Potassium channel, inwardly rectifying subfamily J member 6)
Gene: KCNJ6

Interactor 2: KCNJ6 (P48542)
G protein-activated inward rectifier potassium channel 2 (GIRK-2) (Inward rectifier K(+) channel Kir3.2) (Potassium channel, inwardly rectifying subfamily J member 6)
Gene: KCNJ6

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 21962516
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IRK~IRK, IRK~IRK_C, IRK_C~IRK_C
Common GO terms GO:0001965 - G-protein alpha-subunit binding
GO:0005242 - inward rectifier potassium channel activity
GO:0005267 - potassium channel activity
GO:0005886 - plasma membrane
GO:0009986 - cell surface
and 11 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 425
Mm

1 425
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Bt
+ Gg
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024