HitPredict

Interactor 1: IRF1 (P15314)
Interferon regulatory factor 1 (IRF-1)
Gene: IRF1

Interactor 2: MYD88 (P22366)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.650

The method score is based on:

Property Details
Experiments 17018642, 7567467, 17273999
Identification Methods anti tag coimmunoprecipitation, fluorescent resonance energy transfer, electrophoretic mobility supershift assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006915 - apoptotic process
GO:0010468 - regulation of gene expression
GO:0032481 - positive regulation of type I interferon production
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 329
Mm

1 296
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024