HitPredict

Interactor 1: ATF2 (P15336)
Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (Activating transcription factor 2) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (HB16) (cAMP response element-binding protein CRE-BP1)
Gene: ATF2

Interactor 2: AF17 (P55198)
Protein AF-17 (ALL1-fused gene from chromosome 17 protein)
Gene: MLLT6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046872 - metal ion binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 505 Hs			1 1093
+	Hs
		568255 ATF7_HUMAN (19-500): 5.33e-94: 295: 54.29		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		876591 CREB5_HUMAN (18-457): 1.49e-64: 219: 35.59		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		568081 JUND_HUMAN (154-425): 2.88e-35: 136: 19.36		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		401708 JUN_HUMAN (131-423): 2.08e-32: 128: 17.78		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		401362 JUN_HUMAN (131-423): 2.08e-32: 128: 17.78		MUC1_HUMAN (314-1082): 1.9e-41: 168: 13.53