Interactor 1: VAV (P15498)
Proto-oncogene vav
Gene: VAV1

Interactor 2: NOTC1 (P46531)
Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: NOTCH1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 23022380
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~SH3_1
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006955 - immune response
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 845
Hs

1 2555
+ Mm
+ Hs

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Last updated: 15 Jul 2024