HitPredict

Interactor 1: RAG1 (P15918)
V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74) [Includes: Endonuclease RAG1 (EC 3.1.-.-); E3 ubiquitin-protein ligase RAG1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAG1)]
Gene: RAG1

Interactor 2: RAG1 (P15918)
V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74) [Includes: Endonuclease RAG1 (EC 3.1.-.-); E3 ubiquitin-protein ligase RAG1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAG1)]
Gene: RAG1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.778

The method score is based on:

Property Details
Experiments 26124138, 19118899
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains RAG1~RAG1, RAG1_imp_bd~zf-C3HC4, RAG1_imp_bd~zf-RAG1
Common GO terms GO:0002250 - adaptive immune response
GO:0002331 - pre-B cell allelic exclusion
GO:0003677 - DNA binding
GO:0004519 - endonuclease activity
GO:0004842 - ubiquitin-protein transferase activity
and 24 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1043
Hs

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Last updated: 15 Jul 2024