Interactor 1: APLP1 (P51693)
Amyloid beta precursor like protein 1 (Amyloid beta (A4) precursor-like protein 1) (Amyloid-like protein 1) (APLP) (APLP-1) [Cleaved into: C30]
Gene: APLP1
Interactor 2: APLP2 (Q06481)
Amyloid beta precursor like protein 2 (APPH) (Amyloid beta (A4) precursor-like protein 2) (Amyloid protein homolog) (Amyloid-like protein 2) (APLP-2) (CDEI box-binding protein) (CDEBP) (Sperm membrane protein YWK-II)
Gene: APLP2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.46 | 1.00 | 0.681 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16193067 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | APP_Cu_bd~APP_Cu_bd, APP_Cu_bd~APP_N, APP_E2~APP_E2, APP_N~APP_N |
| Common GO terms | GO:0005886 - plasma membrane GO:0007409 - axonogenesis GO:0007417 - central nervous system development GO:0008201 - heparin binding GO:0046914 - transition metal ion binding |
| Homologous interactions | 12 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025